Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training
|
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
| ClinicalTrials.gov Identifier: NCT02188849 |
|
Recruitment Status :
Completed
First Posted : July 14, 2014
Results First Posted : October 30, 2015
Last Update Posted : October 30, 2015
|
- Study Details
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
| Study Type | Interventional |
|---|---|
| Study Design | Allocation: Randomized; Intervention Model: Parallel Assignment; Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor); Primary Purpose: Treatment |
| Condition |
Muscle Weakness |
| Interventions |
Other: Resistance exercise training Drug: Creatine |
| Enrollment | 50 |
| Recruitment Details | |
| Pre-assignment Details |
| Arm/Group Title | Creatine | Placebo |
|---|---|---|
 Arm/Group Description |
Creatine 5 g/ day Resistance exercise training: All participants will be subjected to resistance training of upper and lower limbs, using elastic bands and tubing and free weights. Training will be calibrated at 60% of one repetition maximum for each muscle group with three sets of 15 repetitions with one minute rest between each set. All exercises will be additionally calibrated to be of moderate intensity according to the Borg scale. The exercise load will be adapted according to the progression of each participant. Creatine: Creatine powder 5 g day |
Maltodextrin 5 g/day to be dissolved in water Resistance exercise training: All participants will be subjected to resistance training of upper and lower limbs, using elastic bands and tubing and free weights. Training will be calibrated at 60% of one repetition maximum for each muscle group with three sets of 15 repetitions with one minute rest between each set. All exercises will be additionally calibrated to be of moderate intensity according to the Borg scale. The exercise load will be adapted according to the progression of each participant. |
| Period Title: Overall Study | ||
| Started | 25 | 25 |
| Completed | 22 | 17 |
| Not Completed | 3 | 8 |
| Reason Not Completed | ||
| Lost to Follow-up | 3 | 8 |
| Arm/Group Title | Creatine | Placebo | Total | |
|---|---|---|---|---|
|
Arm/Group Description |
Creatine 5 g/ day Resistance exercise training: All participants will be subjected to resistance training of upper and lower limbs, using elastic bands and tubing and free weights. Training will be calibrated at 60% of one repetition maximum for each muscle group with three sets of 15 repetitions with one minute rest between each set. All exercises will be additionally calibrated to be of moderate intensity according to the Borg scale. The exercise load will be adapted according to the progression of each participant. Creatine: Creatine powder 5 g day |
Maltodextrin 5 g/day to be dissolved in water Resistance exercise training: All participants will be subjected to resistance training of upper and lower limbs, using elastic bands and tubing and free weights. Training will be calibrated at 60% of one repetition maximum for each muscle group with three sets of 15 repetitions with one minute rest between each set. All exercises will be additionally calibrated to be of moderate intensity according to the Borg scale. The exercise load will be adapted according to the progression of each participant. |
Total of all reporting groups | |
| Overall Number of Baseline Participants | 25 | 25 | 50 | |
|
Baseline Analysis Population Description |
[Not Specified]
|
|||
|
Age, Continuous
Mean (Standard Deviation) Unit of measure: Years |
||||
| Number Analyzed | 25 participants | 25 participants | 50 participants | |
| 67.5 (4.5) | 68.1 (4.9) | 67.8 (4.7) | ||
|
Sex: Female, Male
Measure Type: Count of Participants Unit of measure: Participants |
||||
| Number Analyzed | 25 participants | 25 participants | 50 participants | |
| Female |
25 100.0%
|
25 100.0%
|
50 100.0%
|
|
| Male |
0 0.0%
|
0 0.0%
|
0 0.0%
|
|
|
Region of Enrollment
Measure Type: Number Unit of measure: Participants |
||||
| Chile | Number Analyzed | 25 participants | 25 participants | 50 participants |
| 25 | 25 | 50 | ||
| Name/Title: | Sandra Hirsch MD |
| Organization: | Institute of Nutrition and Food Technology University of Chile |
| Phone: | +56 229781485 |
| EMail: | shirsch@inta.uchile.cl |
| Responsible Party: | Daniel Bunout, University of Chile |
| ClinicalTrials.gov Identifier: | NCT02188849 |
| Other Study ID Numbers: |
Creatine elderly Creatine INTA ( Other Identifier: INTA U de Chile ) |
| First Submitted: | July 10, 2014 |
| First Posted: | July 14, 2014 |
| Results First Submitted: | October 1, 2015 |
| Results First Posted: | October 30, 2015 |
| Last Update Posted: | October 30, 2015 |