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Trial record 66 of 298 for:    "Ankylosing spondylitis"

Exercise Therapy Program in Ankylosing Spondylitis Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01690273
Recruitment Status : Completed
First Posted : September 21, 2012
Results First Posted : October 20, 2016
Last Update Posted : October 20, 2016
Sponsor:
Information provided by (Responsible Party):
Andrea Lopes Gallinaro, University of Sao Paulo

Study Type Interventional
Study Design Allocation: Randomized;   Intervention Model: Parallel Assignment;   Masking: None (Open Label);   Primary Purpose: Supportive Care
Condition Ankylosing Spondylitis
Interventions Other: mobility exercise
Other: mobility and elastic resistance exercise
Enrollment 55
Recruitment Details Two hundred nine consecutive patients from the division of rheumatology outpatient clinic of the university hospital (Clinics Hospital of University Medicine School of Sao Paulo) diagnosed with AS according to the modified New York criteria, were invited to participate. Fifty Five individuals were randomly allocated into three groups
Pre-assignment Details Seventy patients did not accepted and 84 did not followed inclusion criteria. Fifty five were allocated into three groups after following the inclusion criteria.
Arm/Group Title Ankylosing Spondylitis Control Mobility in Ankylosing Spondylitis Mobility and Elastic Resistance Exercise in AS
Hide Arm/Group Description control group, no intervention in ankylosing spondylitis patients

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility, plus elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Period Title: Overall Study
Started 18 17 20
Completed 18 17 20
Not Completed 0 0 0
Arm/Group Title Ankylosing Spondylitis Control Stretching in AS Elastic Resistance Exercise in AS Total
Hide Arm/Group Description Following a randomization, patients from control group stays during sixteen weeks only with medical treatment.

stretching exercises

stretching exercise: 30 minutes, twice a week for sixteen weeks.

stretching and elastic resistance exercises

stretching and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour) for sixteen weeks.

Total of all reporting groups
Overall Number of Baseline Participants 18 17 20 55
Hide Baseline Analysis Population Description
[Not Specified]
Age, Continuous  
Mean (Standard Deviation)
Unit of measure:  Years
Number Analyzed 18 participants 17 participants 20 participants 55 participants
47.1  (10.8) 49.2  (13.1) 48.3  (11.1) 48.2  (11.7)
Sex: Female, Male  
Measure Type: Count of Participants
Unit of measure:  Participants
Number Analyzed 18 participants 17 participants 20 participants 55 participants
Female
3
  16.7%
2
  11.8%
2
  10.0%
7
  12.7%
Male
15
  83.3%
15
  88.2%
18
  90.0%
48
  87.3%
Race (NIH/OMB)  
Measure Type: Count of Participants
Unit of measure:  Participants
Number Analyzed 18 participants 17 participants 20 participants 55 participants
American Indian or Alaska Native
0
   0.0%
0
   0.0%
0
   0.0%
0
   0.0%
Asian
0
   0.0%
0
   0.0%
0
   0.0%
0
   0.0%
Native Hawaiian or Other Pacific Islander
0
   0.0%
0
   0.0%
0
   0.0%
0
   0.0%
Black or African American
0
   0.0%
0
   0.0%
0
   0.0%
0
   0.0%
White
13
  72.2%
12
  70.6%
13
  65.0%
38
  69.1%
More than one race
5
  27.8%
5
  29.4%
7
  35.0%
17
  30.9%
Unknown or Not Reported
0
   0.0%
0
   0.0%
0
   0.0%
0
   0.0%
1.Primary Outcome
Title FUNCTIONAL INDEX
Hide Description BASFI - Bath ankylosing spondylitis functional index. A scale from 0 to 10 (lower scores means better functional capacity), results are measured by mean and standard deviation.
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group with AS patients and no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: units on a scale
baseline 3.4  (2.7) 4.3  (1.9) 3.2  (2.6)
16 weeks 4.5  (2.5) 4.0  (2.2) 2.2  (2.0)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.13
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.99
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.11
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.9913
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.0427
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.1856
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
2.Primary Outcome
Title Mobility Index
Hide Description Bath ankylosing spondylitis motion index. A mean of five mobility measures committed by Ankylosing Spondylitis disease. Higher results means higher limitations in mobility (units of measure from 0 to 10)
Time Frame Baseline and 16 weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group with AS patients and no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: units on a scale from 0 to 10
baseline 4.3  (2) 5.3  (2) 4.5  (2.1)
16 weeks 4.6  (2.0) 4.8  (2.1) 4.0  (2.1)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.04
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.0002
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.0002
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 1
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.935
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.876
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
3.Primary Outcome
Title Disease Activity Index
Hide Description BASDAI - Bath ankylosing spondylitis disease activity index. Scale from 0 to 6. Higher scores means worst disease activity. Numbers are expressed in average (SD)
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
Following a randomization, patients from control group stays during sixteen weeks only with medical treatment.

mobility exercises

mobility exercise: 30 minutes, twice a week for sixteen weeks.

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour) for sixteen weeks.

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: units on a scale
baseline 2  (1) 2.6  (1.1) 2.1  (1.4)
16 weeks 3.2  (2.0) 2.9  (1.4) 1.7  (1.4)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.004
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.87
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.83
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.989
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.022
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.119
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
4.Primary Outcome
Title Ankylosing Spondylitis Disease Activity Scale -Disease Activity
Hide Description Scores vary from 0 to 10, and higher than 4 scores are indicative of disease activity. Data are expressed by means and SD
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: units on a scale
baseline 1.8  (0.7) 1.7  (0.7) 1.5  (0.7)
16 weeks 2.2  (0.8) 1.6  (0.7) 1.4  (0.7)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.09
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.99
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.94
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.213
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.007
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.900
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
5.Primary Outcome
Title Global Evaluation Self Reported
Hide Description Bath Ankylosing Spondylitis Global is a self reported global score varying from 0 to 10. Higher scores means worst health evaluation. Expressed by means and standard deviation.
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Median (Standard Deviation)
Unit of Measure: units on a scale
baseline 3.6  (1.9) 5.0  (2.3) 4.1  (2.6)
16 weeks 5.6  (2.4) 4.7  (2.2) 3.4  (2.5)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.003
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.99
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.69
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.874
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.057
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.526
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
6.Secondary Outcome
Title Thoracolumbar Mobility
Hide Description Thoracolumbar rotation Pavelka. Measured with a tape in centimeters. Higher number means better thoracolumbar rotation
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: Centimeters
baseline 1.9  (1.5) 1.4  (0.9) 1.6  (1.1)
16 weeks 1.7  (0.9) 2.1  (1.0) 2.6  (1.1)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.853
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.016
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.000
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.889
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.098
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.645
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
7.Secondary Outcome
Title Pain Scale
Hide Description Pain was evaluated in a visual analogue scale (VAS) from 0 to 10. higher scores means much pain. Data was expressed by means and standard deviation.
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: units on a scale
baseline 1.8  (1.8) 2.5  (1.9) 2.0  (1.9)
16 weeks 2.3  (2.7) 2.4  (1.5) 2.0  (1.9)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.07
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.13
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.97
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 1
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.338
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.476
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
8.Secondary Outcome
Title Stiffness Scale
Hide Description Stiffness was measured by an VAS varying from 0 to 10. Higher scores means worst stiffness. Data are expressed by mean and SD.
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: units on a scale
baseline 3.1  (2.6) 3.1  (2.2) 3.1  (2.4)
16 weeks 4.3  (2.6) 4.2  (2.0) 2.8  (2.0)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.88
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.99
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 1
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 1
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.995
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.985
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
9.Secondary Outcome
Title Short Form-12 (PCS)
Hide Description Quality of life was analyzed in a physical component score varying from 0 (lowest level of health) to 100 (highest level of health) scale. Data are expressed by mean and SD.
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: units on a scale
baseline 42.3  (7.4) 38.8  (8.0) 43.9  (8.5)
16 weeks 41.9  (8.8) 40.9  (10.6) 44.8  (8.8)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.9
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.7
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.99
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.999
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.900
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.739
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
10.Secondary Outcome
Title Short Form-12 (MCS)
Hide Description Quality of life was analyzed in a mental component score varying from 0 (lowest level of health) to 100 (highest level of health). Data are expressed by mean and SD.
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: units on a scale
baseline 51.8  (10.7) 45.7  (11.6) 47.1  (13.5)
16 weeks 52.1  (9.7) 46.0  (10.8) 51.6  (12.4)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 1
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 1
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.37
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.618
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 1
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.689
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
11.Secondary Outcome
Title MASES
Hide Description Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) score varying from 0 to 13. Where 0 is no painful point reported and 13 is all tender points reported as painful. Data are expressed by means and standard deviation
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: Number of painful tender points
baseline 0.7  (1.4) 1.5  (3.4) 0.8  (1.7)
16 weeks 1.3  (1.9) 1.1  (1.7) 0.7  (1.5)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.8
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.97
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.99
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.999
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.929
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.980
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
12.Secondary Outcome
Title Chin-coronoid Distance
Hide Description lateral rotation of the head (chin-coronoid distance) was measured with a tape in centimeters. Highest score means better lateral rotation mobility. Data are expressed by means and standard deviation
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: Centimeters
baseline 9.9  (2.7) 14.2  (5.6) 10.9  (3.6)
16 weeks 10.0  (2.5) 9.5  (2.3) 9.2  (1.6)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 1
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.000
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.350
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.997
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.970
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.999
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
13.Secondary Outcome
Title Tragus-coronoid Distance
Hide Description lateral flexion of the head (tragus-coronoid distance) was measured with a tape in centimeters. Highest score means better lateral flexion mobility of the head.Data are expressed by means and standard deviation
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: Centimeters
baseline 9.9  (2.7) 12.3  (4.0) 9.7  (3.3)
16 weeks 10.1  (2.2) 9.0  (2.0) 8.8  (2.0)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.997
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.000
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.503
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.814
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.643
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.999
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
14.Secondary Outcome
Title Finger Floor Distance
Hide Description Distance between third finger of the hand and the floor while in lumbar flexion. It was measured with a tape in centimeters. Highest score means better torso flexion mobility. Data are expressed by means and standard deviation
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: Centimeters
baseline 27.6  (13.3) 27.1  (13.7) 23.7  (12.0)
16 weeks 29.5  (13.6) 24.2  (13.3) 20.3  (11.8)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.787
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.408
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.157
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.835
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.256
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.935
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
15.Secondary Outcome
Title Chest Expansion
Hide Description Chest expansion was measured with a tape in centimeters between inspiration and breathing exhaling. Highest score means better chest expansion. Data are expressed by means and standard deviation.
Time Frame Baseline and 16 Weeks
Hide Outcome Measure Data
Hide Analysis Population Description
[Not Specified]
Arm/Group Title Ankylosing Spondylitis Control Mobility in AS Mobility Plus Elastic Resistance Exercise in AS
Hide Arm/Group Description:
control group AS patients with no exercise

mobility exercises

mobility exercise: 30 minutes, twice a week

mobility and elastic resistance exercises

mobility and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour)

Overall Number of Participants Analyzed 18 17 20
Mean (Standard Deviation)
Unit of Measure: Centimeters
baseline 2.8  (1.3) 2.8  (1.2) 3.6  (1.7)
16 weeks 3.0  (1.9) 3.3  (1.2) 4.3  (1.9)
Show Statistical Analysis 1 Hide Statistical Analysis 1
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.978
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 2 Hide Statistical Analysis 2
Statistical Analysis Overview Comparison Group Selection Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.169
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 3 Hide Statistical Analysis 3
Statistical Analysis Overview Comparison Group Selection Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.002
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 4 Hide Statistical Analysis 4
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.993
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 5 Hide Statistical Analysis 5
Statistical Analysis Overview Comparison Group Selection Ankylosing Spondylitis Control, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.105
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Show Statistical Analysis 6 Hide Statistical Analysis 6
Statistical Analysis Overview Comparison Group Selection Mobility in AS, Mobility Plus Elastic Resistance Exercise in AS
Comments [Not Specified]
Type of Statistical Test Superiority or Other
Comments [Not Specified]
Statistical Test of Hypothesis P-Value 0.335
Comments [Not Specified]
Method Mixed Models Analysis
Comments [Not Specified]
Time Frame during 16 weeks
Adverse Event Reporting Description A baseline evaluation was done and another after 16 weeks
 
Arm/Group Title Ankylosing Spondylitis Control Stretching in AS Elastic Resistance Exercise in AS
Hide Arm/Group Description Following a randomization, patients from control group stays during sixteen weeks only with medical treatment.

stretching exercises

stretching exercise: 30 minutes, twice a week for sixteen weeks.

stretching and elastic resistance exercises

stretching and elastic resistance exercise: 30 minutes, twice a week each exercises group. (total 1 hour) for sixteen weeks.

All-Cause Mortality
Ankylosing Spondylitis Control Stretching in AS Elastic Resistance Exercise in AS
Affected / at Risk (%) Affected / at Risk (%) Affected / at Risk (%)
Total   --/--   --/--   --/-- 
Show Serious Adverse Events Hide Serious Adverse Events
Ankylosing Spondylitis Control Stretching in AS Elastic Resistance Exercise in AS
Affected / at Risk (%) Affected / at Risk (%) Affected / at Risk (%)
Total   0/18 (0.00%)   0/17 (0.00%)   0/20 (0.00%) 
Show Other (Not Including Serious) Adverse Events Hide Other (Not Including Serious) Adverse Events
Frequency Threshold for Reporting Other Adverse Events 0%
Ankylosing Spondylitis Control Stretching in AS Elastic Resistance Exercise in AS
Affected / at Risk (%) Affected / at Risk (%) Affected / at Risk (%)
Total   0/18 (0.00%)   0/17 (0.00%)   0/20 (0.00%) 
Certain Agreements
All Principal Investigators ARE employed by the organization sponsoring the study.
Results Point of Contact
Name/Title: Andrea Lopes Gallinaro; Researcher
Organization: Universidade Sao Paulo
Phone: 55112601 ext 8022
Responsible Party: Andrea Lopes Gallinaro, University of Sao Paulo
ClinicalTrials.gov Identifier: NCT01690273     History of Changes
Other Study ID Numbers: 8206212
First Submitted: September 18, 2012
First Posted: September 21, 2012
Results First Submitted: January 27, 2016
Results First Posted: October 20, 2016
Last Update Posted: October 20, 2016