Creatine Augmentation in Veterans With SSRI-Resistant Major Depression
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|ClinicalTrials.gov Identifier: NCT01175616|
Recruitment Status : Withdrawn (Study withdrawn from ClinicalTrials.gov.)
First Posted : August 5, 2010
Last Update Posted : August 15, 2016
University of Utah
Information provided by (Responsible Party):
Douglas Kondo, MD, University of Utah
No Study Results Posted on ClinicalTrials.gov for this Study
Study was withdrawn before participants were enrolled.
|Recruitment Status :||Withdrawn|
|Actual Primary Completion Date :||April 2014|
|Actual Study Completion Date :||April 2014|
Lyoo IK, Yoon S, Kim TS, Hwang J, Kim JE, Won W, Bae S, Renshaw PF. A randomized, double-blind placebo-controlled trial of oral creatine monohydrate augmentation for enhanced response to a selective serotonin reuptake inhibitor in women with major depressive disorder. Am J Psychiatry. 2012 Sep;169(9):937-945. doi: 10.1176/appi.ajp.2012.12010009.
Kondo DG, Sung YH, Hellem TL, Fiedler KK, Shi X, Jeong EK, Renshaw PF. Open-label adjunctive creatine for female adolescents with SSRI-resistant major depressive disorder: a 31-phosphorus magnetic resonance spectroscopy study. J Affect Disord. 2011 Dec;135(1-3):354-61. doi: 10.1016/j.jad.2011.07.010. Epub 2011 Aug 9.
Allen PJ, D'Anci KE, Kanarek RB, Renshaw PF. Sex-specific antidepressant effects of dietary creatine with and without sub-acute fluoxetine in rats. Pharmacol Biochem Behav. 2012 Jun;101(4):588-601. doi: 10.1016/j.pbb.2012.03.005. Epub 2012 Mar 10.