Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
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|ClinicalTrials.gov Identifier: NCT01143519|
Recruitment Status : Enrolling by invitation
First Posted : June 14, 2010
Last Update Posted : August 13, 2018
National Institute of Environmental Health Sciences (NIEHS)
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( National Institute of Environmental Health Sciences (NIEHS) )
No Study Results Posted on ClinicalTrials.gov for this Study
|Recruitment Status :||Enrolling by invitation|
|Primary Completion Date :||No date given|
|Study Completion Date :||No date given|
Bond GL, Hu W, Bond EE, Robins H, Lutzker SG, Arva NC, Bargonetti J, Bartel F, Taubert H, Wuerl P, Onel K, Yip L, Hwang SJ, Strong LC, Lozano G, Levine AJ. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell. 2004 Nov 24;119(5):591-602.
Menendez D, Inga A, Resnick MA. The expanding universe of p53 targets. Nat Rev Cancer. 2009 Oct;9(10):724-37. doi: 10.1038/nrc2730. Review.