Comparing Blood Vessel Endothelial Function in HIV-Infected People and Matched HIV-Uninfected People

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00919724
Recruitment Status : Completed
First Posted : June 12, 2009
Results First Posted : June 30, 2014
Last Update Posted : July 15, 2014
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by (Responsible Party):
Samir K Gupta, MD, MS, National Heart, Lung, and Blood Institute (NHLBI)

Study Type: Observational
Study Design: Observational Model: Case Control;   Time Perspective: Prospective
Condition: HIV Infection

  Participant Flow

Recruitment Details
Key information relevant to the recruitment process for the overall study, such as dates of the recruitment period and locations
No text entered.

Pre-Assignment Details
Significant events and approaches for the overall study following participant enrollment, but prior to group assignment
No text entered.

Reporting Groups
HIV-Infected HIV-infected participants who are not currently receiving antiretroviral medications
HIV-Uninfected HIV-uninfected participants matched in age, sex, smoking status, and height to the HIV-infected participants

Participant Flow:   Overall Study
    HIV-Infected   HIV-Uninfected
STARTED   45   44 
COMPLETED   45   44 

  Baseline Characteristics

  Outcome Measures

1.  Primary:   Endothelial Function (Brachial Artery Reactivity)   [ Time Frame: Single measurement ]

  Serious Adverse Events

  Other Adverse Events

  Limitations and Caveats

Limitations of the study, such as early termination leading to small numbers of participants analyzed and technical problems with measurement leading to unreliable or uninterpretable data
No text entered.

  More Information

Certain Agreements:  
All Principal Investigators ARE employed by the organization sponsoring the study.

Results Point of Contact:  
Name/Title: Samir K. Gupta, MD, MS
Organization: Indiana University School of Medicine
phone: 317-274-7926

Responsible Party: Samir K Gupta, MD, MS, National Heart, Lung, and Blood Institute (NHLBI) Identifier: NCT00919724     History of Changes
Other Study ID Numbers: 661
R01HL095149 ( U.S. NIH Grant/Contract )
First Submitted: June 11, 2009
First Posted: June 12, 2009
Results First Submitted: May 28, 2014
Results First Posted: June 30, 2014
Last Update Posted: July 15, 2014