Advanced MRI in Blast-related TBI
|ClinicalTrials.gov Identifier: NCT00785304|
Recruitment Status : Unknown
Verified December 2014 by David Brody, MD, PhD, Washington University School of Medicine.
Recruitment status was: Enrolling by invitation
First Posted : November 5, 2008
Last Update Posted : December 10, 2014
Washington University School of Medicine
Landstuhl Regional Medical Center
U.S. Army Medical Research and Materiel Command
Information provided by (Responsible Party):
David Brody, MD, PhD, Washington University School of Medicine
Results Submitted - Not Posted on ClinicalTrials.gov
Results information has been submitted to ClinicalTrials.gov by the sponsor or investigator, but is not yet publicly available (or "posted") on ClinicalTrials.gov. The submitted information may not be available if it is pending Quality Control (QC) Review by the National Library of Medicine (NLM) or if issues identified during QC review are being addressed or corrected by the sponsor or investigator. NLM's limited QC review assesses for apparent errors, deficiencies, or inconsistencies. NLM staff do not verify the scientific validity or relevance of the submitted information.
|Recruitment Status :||Unknown|
|Actual Primary Completion Date :||July 2011|
|Estimated Study Completion Date :||July 2016|
|Submission Cycle||Results Submitted to ClinicalTrials.gov||Results Returned after Quality Control Review|
|1||May 6, 2016||June 13, 2016|
Publications of Results:
Mac Donald CL, Johnson AM, Cooper D, Nelson EC, Werner NJ, Shimony JS, Snyder AZ, Raichle ME, Witherow JR, Fang R, Flaherty SF, Brody DL. Detection of blast-related traumatic brain injury in U.S. military personnel. N Engl J Med. 2011 Jun 2;364(22):2091-100. doi: 10.1056/NEJMoa1008069.
Mac Donald C, Johnson A, Cooper D, Malone T, Sorrell J, Shimony J, Parsons M, Snyder A, Raichle M, Fang R, Flaherty S, Russell M, Brody DL. Cerebellar white matter abnormalities following primary blast injury in US military personnel. PLoS One. 2013;8(2):e55823. doi: 10.1371/journal.pone.0055823. Epub 2013 Feb 7.
Han K, Mac Donald CL, Johnson AM, Barnes Y, Wierzechowski L, Zonies D, Oh J, Flaherty S, Fang R, Raichle ME, Brody DL. Disrupted modular organization of resting-state cortical functional connectivity in U.S. military personnel following concussive 'mild' blast-related traumatic brain injury. Neuroimage. 2014 Jan 1;84:76-96. doi: 10.1016/j.neuroimage.2013.08.017. Epub 2013 Aug 20.