Evaluating the Effects of Supplemental Vitamin C on Infant Lung Function in Pregnant Smoking Women
|ClinicalTrials.gov Identifier: NCT00632476|
Recruitment Status : Completed
First Posted : March 10, 2008
Last Update Posted : September 4, 2013
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Environmental Health Sciences (NIEHS)
Information provided by (Responsible Party):
Cynthia McEvoy, National Heart, Lung, and Blood Institute (NHLBI)
No Study Results Posted on ClinicalTrials.gov for this Study
|Recruitment Status :||Completed|
|Actual Primary Completion Date :||July 2011|
|Actual Study Completion Date :||July 2012|
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Shorey-Kendrick LE, McEvoy CT, Ferguson B, Burchard J, Park BS, Gao L, Vuylsteke BH, Milner KF, Morris CD, Spindel ER. Vitamin C Prevents Offspring DNA Methylation Changes Associated with Maternal Smoking in Pregnancy. Am J Respir Crit Care Med. 2017 Sep 15;196(6):745-755. doi: 10.1164/rccm.201610-2141OC.
McEvoy CT, Schilling D, Clay N, Jackson K, Go MD, Spitale P, Bunten C, Leiva M, Gonzales D, Hollister-Smith J, Durand M, Frei B, Buist AS, Peters D, Morris CD, Spindel ER. Vitamin C supplementation for pregnant smoking women and pulmonary function in their newborn infants: a randomized clinical trial. JAMA. 2014 May;311(20):2074-82. doi: 10.1001/jama.2014.5217.
Didenco S, Gillingham MB, Go MD, Leonard SW, Traber MG, McEvoy CT. Increased vitamin E intake is associated with higher alpha-tocopherol concentration in the maternal circulation but higher alpha-carboxyethyl hydroxychroman concentration in the fetal circulation. Am J Clin Nutr. 2011 Feb;93(2):368-73. doi: 10.3945/ajcn.110.008367. Epub 2010 Dec 15.