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Levetiracetam Versus Carbamazepine in Post-Stroke Late Onset Crisis (EpIc)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00542802
Recruitment Status : Unknown
Verified May 2008 by Scienze Neurologiche Ospedaliere.
Recruitment status was:  Recruiting
First Posted : October 12, 2007
Last Update Posted : May 30, 2008
Information provided by:
Scienze Neurologiche Ospedaliere

No Study Results Posted on for this Study
Recruitment Status : Unknown
Estimated Primary Completion Date : June 2009
Estimated Study Completion Date : June 2009
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- Klitgaard H, Pitkanen A, Antiepileptogenesis, neuroprotection, and disease modification in the treatment of epilepsy: focus on levetiracetam. Epileptic disorder 2003; 5:S9-S16 - Kraemer G, Eldrich P. Levetiracetam in Elderly patients with epilepsy - The American Eplepsy Society and The American Clinical Neurophysiology Society - Joint Meeting November 30-December 5, 2001 - Krakow K, Walker M, Otoul C, Sander JWAS. Long-term continuation of Levetiracetam in patients with refractory epilepsy. Neurology 2001;56:1772-1774 - Krauss GL, Abou-khalil B, Sheth SG. Efficacy of levetiracetam for treatment fo drug-resistant generalised epilepsy. Epilepsia 2001;42(suppl 7):181 - Krauss GL, Betts T, Abou-Khalil B, Bergey G, Yarrow H, Miller A. Levetiracetam treatment of idiopathic generalised epilepsy. Seizure 2003;12:617-620
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- Madeja M., Margineanu D.G., Gorji A., Siep E., Boerrigter P., Klitgaard H., Et Al. Reduction Of Voltage-Operated Potassium Currents By Levetiracetam: A Novel Antiepileptic Mechanism Of Action? - Neuropharmacology Oct-2003. 45(5):661-671. - Margineau D. G., Klitgaard Henrik Levetiracetam - Mechanism of action - Antiepilectic drugs, 5th edition. Edited by R.H. Levy, R.H. Mattson, B.S. Meldrum, and E.Perucca. Philadelphia: Lippincott Williams & Wilkins, 2002 - Margineau DG, Klitgaard H Inhibition of neural hyperynchrony in vitro differentiates levetiracetam fro classical antiepileptic drugs Pharmacol. Research 2000; 42(4): 281-285 - Marson AG, Hutton JL, Leach JP. Levetiracetam, Oxcarbazepine, Remacemide and zonisamide for drug resistant localization-related epilepsy: a systematic review. Epilepsy Res 2001;46:259-270
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- Ben-Menachem E and Falter U for the European Levetiracetam Group. Efficacy and tolerability of levetiracetam 3000 mg/d in subjects with refractory partial seizures: a multicenter, double-blind, responder-selected study evaluating monotherapy. Epilepsia 2000; 41:1276-83 - A multicenter, double-blind, randomized, parallel group study comparing the safety and efficacy of 3,000 mg per day of Levetiracetam to 1,000 mg per day of Valproate used as monotherapy in epileptic subjects with complex partial seizures. 1999. UCB Study Number N00158. UCB protocol RPCE98B2501 - A long-term multicenter follow-up study of the safety and efficacy of oral 500 mg tablets ucb L059: open treatment at individualized doses up to 4000 mg daily in subjects with epilepsy. UCB Study Number N129 UCB Report RRCE01J1405
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