Rolipram to Treat Multiple Sclerosis
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|ClinicalTrials.gov Identifier: NCT00011375|
Recruitment Status : Completed
First Posted : February 19, 2001
Last Update Posted : March 4, 2008
National Institute of Neurological Disorders and Stroke (NINDS)
Information provided by:
National Institutes of Health Clinical Center (CC)
No Study Results Posted on ClinicalTrials.gov for this Study
|Recruitment Status :||Completed|
|Primary Completion Date :||No date given|
|Estimated Study Completion Date :||April 2004|
Sommer N, Löschmann PA, Northoff GH, Weller M, Steinbrecher A, Steinbach JP, Lichtenfels R, Meyermann R, Riethmüller A, Fontana A, et al. The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis. Nat Med. 1995 Mar;1(3):244-8.
Haskó G, Szabó C, Németh ZH, Salzman AL, Vizi ES. Suppression of IL-12 production by phosphodiesterase inhibition in murine endotoxemia is IL-10 independent. Eur J Immunol. 1998 Feb;28(2):468-72.