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Multimodal Treatment Study of Children With Attention Deficit and Hyperactivity Disorder (MTA) (MTA)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00000388
Recruitment Status : Completed
First Posted : November 3, 1999
Last Update Posted : September 29, 2015
National Institute of Mental Health (NIMH)
Information provided by:
NYU Langone Health

No Study Results Posted on for this Study
Recruitment Status : Completed
Primary Completion Date : No date given
Study Completion Date : November 1999
Publications of Results:
Arnold, L. E., Abikoff, H. B., Cantwell, D. P., Conners, C. K., Elliott, G. R., Greenhill, L. L.,Hechtman, L., Hinshaw, S.P., Hoza B., Jensen, P.S., Kraemer, H.C, March, J.S., Newcorn, J.H., Pelham, W.E., Richters, J.E., Schiller, E., Severe, J.B., Swanson, J.M., Vereen, D., Wells, K.C. (1997). NIMH collaborative multimodal treatment study of children with ADHD (MTA): Design, methodology, and protocol evolution. Journal of Attention Disorders, 2(3), 141-158.
Hinshaw, S. P., March, J. S., Abikoff, H., Arnold, L. E., Cantwell, D. P., Conners, C. K., . . . Wigal, T. (1997). Comprehensive assessment of childhood attention-deficit hyperactivity disorder in the context of a multisite, multimodal clinical trial. Journal of Attention Disorders, 1(4), 217-234.
Arnold, L. E., Elliott, M., Lindsay, R. L., Molina, B., Cornelius, M. D., Vitiello, B., . . . Wells, K. (2005). Gestational and postnatal tobacco smoke exposure as predictor of ADHD, comorbid ODD/CD, and treatment response in the MTA. Clinical Neuroscience Research, 5(5-6), 295-306.

Other Publications:
Marcus, S. M., & Gibbons, R. D. (2001). Estimating the efficacy of receiving treatment in randomized clinical trials with noncompliance. Health Services and Outcomes Research Methodology, 2(3-4), 247-258.
Newcorn, J. H. (2004). Comorbidity of ADHD and disruptive behavior disorders: Prevalence, impact, and management options. Drug Benefit Trends, 16(8), 431-436.
Galanter, C. A., Pagar, D. L., Davies, M., Li, W., Carlson, G. A., Abikoff, H. B., . . . Jensen, P. S. (2005). ADHD and manic symptoms: Diagnostic and treatment implications. Clinical Neuroscience Research, 5(5-6), 283-294.
Hechtman, L., Etcovitch, J., Platt, R., Arnold, L. E., Abikoff, H. B., Newcorn, J. H., . . . Wigal, T. (2005). Does multimodal treatment of ADHD decrease other diagnoses? Clinical Neuroscience Research, 5(5-6), 273-282.
Santosh, P. J., Taylor, E., Swanson, J., Wigal, T., Chuang, S., Davies, M., . . . Posner, M. (2005). Refining the diagnoses of inattention and overactivity syndromes: A reanalysis of the multimodal treatment study of attention deficit hyperactivity disorder (ADHD) based on ICD-10 criteria for hyperkinetic disorder. Clinical Neuroscience Research, 5(5-6), 307-314.

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