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The Suitability of Sniff Dog as a Tool in Screening Tumors

This study is currently recruiting participants. (see Contacts and Locations)
Verified January 2014 by Central South University
Information provided by (Responsible Party):
Chang-Qing Gao, Central South University Identifier:
First received: January 25, 2014
Last updated: January 28, 2014
Last verified: January 2014

January 25, 2014
January 28, 2014
January 2014
March 2014   (Final data collection date for primary outcome measure)
Sensitivity and specificity in screening cancer patients [ Time Frame: up to 5 years ]
The results that obtained from the dogs will be compared with these of the pathological examinations. Sensitivity = the No. of patients identified by the dogs as cancers / the No. of patients suffering from cancer confirmed by pathological examination. Specificity = No. of subjects signaled by the dog as non-cancers / No. of subjects confirmed by pathological examination or the currently used methods as non-cancer subjects or at the end of the study, 5 years later still without cancer.
Same as current
No Changes Posted
Behavior patterns of sniff dogs to different diseases [ Time Frame: up to 5 years ]
The behavior (lying before the tank for positive, neglecting the tanks) of the dog will be recorded and compared with the results of the pathological examination.
Same as current
The substances used by the sniff dogs to identifying tumors [ Time Frame: up to 5 years ]
GCMS etc will be used to compare the volatile compounds between the sera from cancers patients and the from normal subjects, the suspected VOCs will be tested by the dog for conformation.
Same as current
The Suitability of Sniff Dog as a Tool in Screening Tumors
The Suitability of Sniff Dog as a Tool in Screening Tumors-- a Prospective Observational Study
Previous studies have demonstrated that sniff dogs can identify cancer patients from healthy subjects through sniffing exhaled breath air or blood or serum or urine or feces. It is hypothesized that sniff dogs may be used as a tool in screening cancer patients in health examination. Trained dogs will sniff serum from participants who are attending the annual health examination to identify potential or high risk subjects, and the results will be compared with the outcome of the traditional health examination, and the high risk subjects will be followed periodically for at least five years.
Not Provided
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Non-Probability Sample
The Third Xiang-Ya Hospital staff members and their adult family members who wish to participate the study.
Not Provided
faculty staff and their adult family members
faculties and their adult family members of the Third Xiang-Ya Hospital

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
March 2019
March 2014   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • old than 20 years
  • currently without cancer diagnosed with pathological examination
  • allow the study team to examine his/her case history and incoming record

Exclusion Criteria:

  • cancer patients with pathological diagnosis
  • who does not allow the study team to examine his/her case history and incoming record
Sexes Eligible for Study: All
20 Years and older   (Adult, Senior)
Contact: Chang-Qing Gao, MD PhD 86 13974981039
Contact: Ya-Qin Wang, MD PhD 86 15274810930
Xiang-Ya 0001
Not Provided
Not Provided
Not Provided
Chang-Qing Gao, Central South University
Chang-Qing Gao
Not Provided
Principal Investigator: Chang-Qing Gao, MD PhD Central South University
Central South University
January 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP