Multifaceted Online Interventions to Increase Clinicians Searching of Current Best Evidence to Answer Clinical Questions (MPFS)

• ClinicalTrials.gov Identifier: NCT02038439
• Recruitment Status: Completed
• First Posted: January 16, 2014
• Last Update Posted: April 8, 2015
• Sponsor: McMaster University
• Collaborator: Canadian Institutes of Health Research (CIHR)
• Information provided by (Responsible Party): McMaster University

Tracking Information

• First Submitted Date: January 15, 2014
• First Posted Date: January 16, 2014
• Last Update Posted Date: April 8, 2015
• Study Start Date: January 2014
• Actual Primary Completion Date: October 2014 (Final data collection date for primary outcome measure)

Current Primary Outcome Measures (submitted: January 15, 2014)

Utilization of evidence-based resources on MPFS as measured by rate of searches/month/user [ Time Frame: 6 months ]

Each clinician participating in the trial has a personal online account in MPFS. When they are signed on their account, the system continuously tracks their searches and utilization of individual resources. We will record their utilization over the full duration of the trial (6 months) and analyze it in the end.

• Original Primary Outcome Measures: Same as current

Current Secondary Outcome Measures (submitted: January 16, 2014)

• Utility (satisfaction in meeting users' information needs) as assessed by the Impact Assessment Measure questionnaire [ Time Frame: 6 months ]
  This Impact Assessment Measure questionnaire will be sent to clinicians after a random sample of searches and completed online for a random sample of searches.
• Use (application of evidence in practice) as assessed by the Impact Assessment Measure questionnaire [ Time Frame: 6 months ]
  This Impact Assessment Measure questionnaire will be sent to clinicians after a random sample of searches and completed online for a random sample of searches.
• Perceived Usefulness in patient care and outcomes as assessed by the Impact Assessment Measure questionnaire [ Time Frame: 6 months ]
  This Impact Assessment Measure questionnaire will be sent to clinicians after a random sample of searches and completed online for a random sample of searches.

Original Secondary Outcome Measures (submitted: January 15, 2014)

Utility, use and perceived usefulness of the evidence accessed, as assessed by the Impact Assessment Measure questionnaire [ Time Frame: 6 months ]

The Impact Assessment Measure is a validated short questionnaire assessing:

• Utility (satisfaction in meeting users' information needs)
• Use (application of evidence in practice)
• and perceived Usefulness in patient care and outcomes This questionnaire will be sent to clinicians after a random sample of searches and completed online for a random sample of searches.

• Current Other Pre-specified Outcome Measures: Not Provided
• Original Other Pre-specified Outcome Measures: Not Provided

Descriptive Information

• Brief Title: Multifaceted Online Interventions to Increase Clinicians Searching of Current Best Evidence to Answer Clinical Questions
• Official Title: Multifaceted Online Interventions to Increase the Quantity and Quality of Searching for Current Best Evidence to Answer Clinical Questions

Brief Summary

Translation of new knowledge from research into evidence-informed health care is a shared obligation of the clinical and the scientific communities. Unfortunately, studies of quality of care continue to show that this goal is substantially unrealized. One main barrier is lack of quick and easy identification, appraisal and synthesis of current best evidence. Clinicians' information have 5 to 8 questions about individual patients per daily shift, but face a large volume of 3000 articles published every day, accessible in many scattered resources.

To address theses problems, McMaster's Health Information Research Unit (Hamilton, Ontario, Canada) has developed and implemented "McMaster Premium LiteratUre Service Federated Search" (MPFS), an online search engine that provides a unique 1-stop search and organized access to current best evidence in daily practice. However additional barriers need to be overcome for clinicians to actually search and use this evidence in their practice. Theses include logistical barriers (time constraints, forgotten questions), as well as educational barriers (eg, lack of awareness of the "architecture" of evidence, limited searching skills, and lack of reference standards among peers for finding best evidence).

This randomized trial seeks to test 3 innovative online interventions among clinicians registered to MPFS to overcome these barriers and increase the quantity and quality of searching for current best evidence to answer clinical questions. These interventions build on effective models for the teaching of clinical skills at the point of care, so that clinicians are facilitated in using the search engine as a clinical tool, and perceive evidence retrieval skills as true clinical skills.

Detailed Description

1. Rationale & Objectives

   One main barrier to achieving evidence-informed care by clinicians is lack of quick and easy identification, appraisal and synthesis of current best evidence. Clinicians' information needs are considerable - but about 3000 articles are published in Medline every day. Numerous evidence-based resources have been developed to filter and process the evidence, but although increasingly used by clinicians, each offer a fragmented and scattered view of information, and none provides comprehensive topic coverage or satisfactory updating.

   To address theses problems, McMaster's Health Information Research Unit (Hamilton, Ontario, Canada) has developed and implemented "McMaster Premium LiteratUre Service Federated Search (MPFS)", an online search engine that provides a unique 1-stop search and organized access to current best evidence in daily practice. MPFS provides both alerts to users about new research in their chosen disciplines, and a novel federated search function, with the particular feature of organizing information according to the "pyramid of evidence-based resources", with the most clinically applicable evidence at the top. Thus MPFS simultaneously retrieves evidence from Studies ("Medline", both filtered and unfiltered, at the bottom), then Systematic reviews; Synopses of studies and systematic reviews (selected for methodological rigor and clinical relevance), and, at the top level, online widely used Summaries (e.g."Best Practice").

   Combining features of the current best evidence-based resources is not enough to increase access and use of current best evidence, as shown by the relatively low utilization of searching features among the hundreds of clinicians currently registered at McMaster University and using the alerting system. Additional well-known barriers that need to be overcome include logistical barriers (time constraints, forgotten questions, and simplicity of using one single albeit limited resource), as well as educational barriers (eg, lack of awareness of the "architecture" of evidence and limits of other single resources, lack of knowledge and experience of what federated searches can offer, limited searching skills, and lack of reference standards among peers for finding best evidence).

2. Hypothesis

   This trial seeks to test 3 innovative online interventions among clinicians registered to MPFS to overcome these barriers and increase the quantity and quality of searching for current best evidence to answer clinical questions. These interventions build on effective models for the teaching of clinical skills at the point of care, so that clinicians are facilitated in using the search engine as a clinical tool, and perceive evidence retrieval skills as true clinical skills.

3. Methods

   1. Study design: Randomized Factorial Controlled Trial.
   2. Setting and Participants: The trial will be conducted among postgraduate and faculty MD registered in MPFS and working in the teaching hospitals and clinics of McMaster University (see eligibility criteria below)
   3. Participating clinicians will be randomized to 3 online interventions (see description below) in a factorial design (A x B x C), whose permutation results in 8 allocation arms (A+B+C, A+B, A+C, B+C, A, B, C, no intervention, see details below)
   4. Randomization: will be computer-generated, stratified training level (post-graduate MD, faculty MD), and baseline frequency of searching for evidence on MPFS. Registrants will be randomly allocated to each study arms. Allocation will be concealed from research staff.
   5. Blinding and control group: Although participants cannot be blinded to the interventions, they will not be told of the different features offered, and all will receive usual searching features of MPFS.
   6. Primary and secondary outcomes (see below).

• Study Type: Interventional
• Study Phase: Not Applicable
• Study Design: Allocation: Randomized; Intervention Model: Factorial Assignment; Masking: Single (Investigator)
• Condition: Physicians Evidence Retrieval Skills

Intervention

• Behavioral: Intervention A - Online Clinical Questions Recorder
  Clinicians allocated to this intervention will receive access to an online recorder for the clinical questions at the point of care. The recorder is accessible across a wide range of devices including phones, tablets, and desktop computers.
• Behavioral: Intervention B - Online Evidence Retrieval Coach
  Clinicians allocated to this intervention will receive online guidance, embedded in the MPFS search engine, in the form of short videos, animations, demos and tips and tricks regarding evidence retrieval.
• Behavioral: Intervention C - Online Audit and Feedback
  Clinicians allocated to this intervention will receive feedback on their current search performance compared to their peers, both online when using MPFS as well as by e-mail.

Study Arms

• Experimental: Interventions: A + B + C

  See Interventions Description. In this arm, clinicians will be offered all 3 online interventions combined:

  • Intervention A - Online Clinical Questions Recorder
  • Intervention B - Online Evidence Retrieval Coach
  • Intervention C - Online Audit and Feedback
  Interventions:

  • Behavioral: Intervention A - Online Clinical Questions Recorder
  • Behavioral: Intervention B - Online Evidence Retrieval Coach
  • Behavioral: Intervention C - Online Audit and Feedback
• Experimental: Interventions A + B

  See Interventions Description. In this arm, clinicians will be offered the 2 following interventions combined:

  • Intervention A - Online Clinical Questions Recorder
  • Intervention B - Online Evidence Retrieval Coach
  Interventions:

  • Behavioral: Intervention A - Online Clinical Questions Recorder
  • Behavioral: Intervention B - Online Evidence Retrieval Coach
• Experimental: Interventions A + C

  See Interventions Description. In this arm, clinicians will be offered the 2 following online interventions combined:

  • Intervention A - Online Clinical Questions Recorder
  • Intervention C - Online Audit and Feedback
  Interventions:

  • Behavioral: Intervention A - Online Clinical Questions Recorder
  • Behavioral: Intervention C - Online Audit and Feedback
• Experimental: Interventions B + C

  See Interventions Description. In this arm, clinicians will be offered the 2 following online interventions combined:

  • Intervention B - Online Evidence Retrieval Coach
  • Intervention C - Online Audit and Feedback
  Interventions:

  • Behavioral: Intervention B - Online Evidence Retrieval Coach
  • Behavioral: Intervention C - Online Audit and Feedback
• Experimental: Intervention A alone

  See Interventions Description. In this arm, clinicians will be offered only the following intervention:

  * Intervention A - Online Clinical Questions Recorder

  Intervention: Behavioral: Intervention A - Online Clinical Questions Recorder
• Experimental: Intervention B alone

  See Interventions Description. In this arm, clinicians will be offered only the following intervention:

  * Intervention B - Online Evidence Retrieval Coach

  Intervention: Behavioral: Intervention B - Online Evidence Retrieval Coach
• Experimental: Intervention C alone

  See Interventions Description. In this arm, clinicians will be offered only the following intervention:

  * Intervention C - Online Audit and Feedback

  Intervention: Behavioral: Intervention C - Online Audit and Feedback
• No Intervention: No intervention
  In this arm, clinicians will be offered non of the 3 online interventions, but will just be using the usual features of the search engine available to all users.

Publications *

• Seguin A, Haynes RB, Carballo S, Iorio A, Perrier A, Agoritsas T. Translating Clinical Questions by Physicians Into Searchable Queries: Analytical Survey Study. JMIR Med Educ. 2020 Apr 20;6(1):e16777. doi: 10.2196/16777.
• Agoritsas T, Iserman E, Hobson N, Cohen N, Cohen A, Roshanov PS, Perez M, Cotoi C, Parrish R, Pullenayegum E, Wilczynski NL, Iorio A, Haynes RB. Increasing the quantity and quality of searching for current best evidence to answer clinical questions: protocol and intervention design of the MacPLUS FS Factorial Randomized Controlled Trials. Implement Sci. 2014 Sep 20;9:125. doi: 10.1186/s13012-014-0125-9.

Recruitment Information

• Recruitment Status: Completed
• Actual Enrollment (submitted: April 7, 2015): 908
• Original Estimated Enrollment (submitted: January 15, 2014): 900
• Actual Study Completion Date: October 2014
• Actual Primary Completion Date: October 2014 (Final data collection date for primary outcome measure)

Eligibility Criteria

Inclusion Criteria:

• All postgraduate and faculty physicians currently registered for more than one month in the MPFS search engine,
• and working in the teaching hospitals and clinics of the Faculty of Health Sciences, McMaster University, Hamilton, Ontario.

Exclusion Criteria:

• Registrants that are no longer working or training at McMaster University,
• Registrants that never logged in MPFS during the last 12 months counting back from the beginning of the trial.

Sex/Gender

• Sexes Eligible for Study: All

• Ages: Child, Adult, Older Adult
• Accepts Healthy Volunteers: No
• Contacts: Contact information is only displayed when the study is recruiting subjects
• Listed Location Countries: Canada

Administrative Information

• NCT Number: NCT02038439
• Other Study ID Numbers: FRN86465
• Has Data Monitoring Committee: No
• U.S. FDA-regulated Product: Not Provided
• IPD Sharing Statement: Not Provided
• Current Responsible Party: McMaster University
• Original Responsible Party: Same as current
• Current Study Sponsor: McMaster University
• Original Study Sponsor: Same as current
• Collaborators: Canadian Institutes of Health Research (CIHR)

Investigators

• Principal Investigator: Thomas Agoritsas, MD; McMaster University

• PRS Account: McMaster University
• Verification Date: April 2015