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Shaping the Health of Adolescents in Zimbabwe (SHAZ!)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT02034214
Recruitment Status : Completed
First Posted : January 13, 2014
Last Update Posted : January 13, 2014
Information provided by (Responsible Party):

January 9, 2014
January 13, 2014
January 13, 2014
February 2006
October 2008   (Final data collection date for primary outcome measure)
Intervention completion [ Time Frame: Within 2 years of follow up ]
Completion of the intervention activities
Same as current
No Changes Posted
  • Unintended pregnancy [ Time Frame: during 2 year follow up ]
    Urine pregnancy test positive during 2 year follow up period, and pregnancy intendedness on self reported survey
  • Incident viral infection with HIV or HSV-2 [ Time Frame: During 2 years of follow up ]
    Blood test for HIV and HSV-2 at each 6 month follow up for 2 years.
Same as current
Not Provided
Not Provided
Shaping the Health of Adolescents in Zimbabwe
Economic Opportunity for Zimbabwean Adolescent Orphans
The SHAZ! study was a randomized trial that compared a package of life skills education, reproductive health care services, and economic livelihood development to a control package of life skills education and reproductive health care services alone. SHAZ! enrolled young women 16 to 19 years old who had been orphaned and who were currently out of school and not infected with HIV. Individuals participated in the project for up to two years.
Not Provided
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Prevention
  • Behavioral: Life skills education
    The life skills curriculum drew upon Stepping Stones and CDC-Zimbabwe Talk Time, developed with input from the target population. It consisted of 14 modules delivered to groups of 25 over 4-6 weeks on: HIV/STI and reproductive health; relationship negotiation; strategies to avoid violence;and identification of safe and risky places in the community. Participants also attended a six-weeks-long home-based care training conducted through Red Cross Zimbabwe, to gain skills on safely caring for people living with HIV.
  • Other: Reproductive health services
    All participants were provided a health screening at every study visit and were treated for treatable STIs and minor ailments. They received condoms, and contraceptive pills or injectable free upon request. Participants who tested positive for HIV were referred to local clinics, where the study team assisted with ART registration including payment for CD4 tests required for enrolment.
  • Behavioral: Economic livelihoods
    The Livelihoods intervention consisted of financial literacy and a choice of vocational training at local training institutes. Courses were 6-months-long, conducted in English, with a practical and a theoretical component. In spite of encouragement to venture outside of accepted gender norms, the most popular courses were hairdressing, garment-making, and receptionist/secretarial and nurse-aid training. Participants who passed developed business plans that were supported with a micro-grant valued at $100US in the form of capital equipment, supplies or additional training.
  • Experimental: Full Intervention
    Life skills education vocational counseling Economic livelihoods reproductive health services social support
    • Behavioral: Life skills education
    • Other: Reproductive health services
    • Behavioral: Economic livelihoods
  • Active Comparator: Education and health services alone
    Life skills education Reproductive health services
    • Behavioral: Life skills education
    • Other: Reproductive health services

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
October 2008
October 2008   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • 16 to 19 years old
  • out of school
  • orphaned
  • willing to participate in intervention activities
  • living in Chitungwiza

Exclusion Criteria:

  • HIV infection
  • currently pregnant
Sexes Eligible for Study: Female
16 Years to 19 Years   (Child, Adult)
Contact information is only displayed when the study is recruiting subjects
R01HD045135 ( U.S. NIH Grant/Contract )
Not Provided
Not Provided
Mi-Suk Kang Dufour, University of California, San Francisco
University of California, San Francisco
  • UZ-UCSF Collaborative Research Programme
  • National Institutes of Health (NIH)
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Principal Investigator: Megan Dunbar, DrPH, MPH Pangea Global AIDS Foundation
University of California, San Francisco
January 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP