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The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2013 by vghtpe user, Taipei Veterans General Hospital, Taiwan.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT02006615
First Posted: December 10, 2013
Last Update Posted: December 10, 2013
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
vghtpe user, Taipei Veterans General Hospital, Taiwan
December 5, 2013
December 10, 2013
December 10, 2013
July 2013
July 2015   (Final data collection date for primary outcome measure)
Repeatable Battery for the Assessment of Neuropsychological Status [ Time Frame: up to 3 months ]
Same as current
No Changes Posted
Reaction time [ Time Frame: up to 3 months ]
Same as current
Not Provided
Not Provided
 
The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory
The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory in Stroke, Parkinson, and Elderly Patients
We hypothesize that ten sessions of repetitive transcranial magnetic stimulation yield ability to upregulate the function of primary motor cortex and prefrontal cortex that play key roles in motor and frontal memory processing.
Excitatory (>3Hz) rTMS could facilitate the brain cortex and neuroplasticity that benefits motor control and working memory when the coil is applied over primary motor cortex or dorsolateral prefrontal gyrus.
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Treatment
Central Nervous System Diseases
Device: rTMS
5Hz rTMS over M1 and inferior frontal lobe
Other Name: Magstim rapid2
  • Experimental: 5Hz rTMS
    rTMS group
    Intervention: Device: rTMS
  • Sham Comparator: Sham rTMS
    Sham stimulation
    Intervention: Device: rTMS
Lai CJ, Wang CP, Tsai PY, Chan RC, Lin SH, Lin FG, Hsieh CY. Corticospinal integrity and motor impairment predict outcomes after excitatory repetitive transcranial magnetic stimulation: a preliminary study. Arch Phys Med Rehabil. 2015 Jan;96(1):69-75. doi: 10.1016/j.apmr.2014.08.014. Epub 2014 Sep 11.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
150
July 2015
July 2015   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Ischemic or hemorrhagic cerebrovascular lesion, Parkinsonism disease, elderly people

Exclusion Criteria:

  • Seizure, metalic implantation, other contra-indications for TMS; Dementia or severe cognitive impairment
Sexes Eligible for Study: All
30 Years to 80 Years   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Taiwan
 
 
NCT02006615
2013-07-011A
Yes
Not Provided
Not Provided
vghtpe user, Taipei Veterans General Hospital, Taiwan
Taipei Veterans General Hospital, Taiwan
Not Provided
Principal Investigator: Po-Yi Tsai, MD Taipei Veterans General Hospital, Taiwan
Taipei Veterans General Hospital, Taiwan
December 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP