Improving Care After Chemotherapy (IMPACT)

• Change from baseline (i.e. first chemotherapy administration visit) in patient-reported psychological distress as measured by the Patient Health Questionnaire-4. [ Time Frame: Approximately 2-3 weeks and 4-6 weeks post-baseline ]
• Change from baseline (i.e. first chemotherapy administration visit) in patient-reported satisfaction with oncology care as measured by the Family Caregiver Satisfaction-patient scale [ Time Frame: Approximately 2-3 weeks and 4-6 weeks post-baseline ]
• Frequency of urgent outpatient Cancer Center visits, emergency department visits, and hospital admissions during six months post-baseline [ Time Frame: Approximately six months post-baseline ]

• Participants with NSCLC, CRC or breast cancer undergoing neoadjuvant or adjuvant chemotherapy will be asked to fill out self-report questionnaires at their first chemotherapy administration visit, in order to measure patient-reported symptoms, psychological distress, and satisfaction with oncology care.
• Participants will then be randomized into one of the two study groups: standard care with proactive phone calls from nurse practitioners or standard care alone.
• Participants assigned to the standard care group will be treated by their care team as would any other cancer patient.
• Participants assigned to the intervention group will receive four proactive phone calls from nurse practitioners designed to discuss symptom burden and management. Proactive phone calls will occur 2-4 days after chemotherapy administration and 5-7 days after chemotherapy administration, during cycles 1 and 2.
• Participants will be asked to fill out the same set of questionnaires during their second and third chemotherapy administration visits, to assess patient-reported symptoms, psychological distress, and satisfaction with oncology care.
• Medical records will be reviewed at 24-weeks following the first chemotherapy administration visit, to evaluate frequency of urgent outpatient cancer center visits, emergency department visits, and hospital admissions that occurred during the study period.

• Non-small Cell Lung Cancer
• Colorectal Cancer
• Breast Cancer

• No Intervention: Standard Care
  Participant will receive standard cancer care
• Experimental: Nursing Intervention
  Participants will receive 4 planned phone calls from nurse practitioners during their first 2 cycles of chemotherapy
  Intervention: Other: Nursing Intervention

Inclusion Criteria:

• Adult (age 18 or older)
• Newly diagnosed stage I-III colorectal cancer, non-small-cell lung cancer, or breast cancer
• Scheduled to receive neoadjuvant chemotherapy (i.e. pre-surgical cancer-directed therapy with curative intent) or adjuvant chemotherapy (i.e. post-surgical cancer-directed therapy with curative intent)
• Able to respond to questions in English

Exclusion Criteria:

• Already received 1 or more cycles of chemotherapy for the current regimen
• Unwilling or unable to participate in the study