This site became the new ClinicalTrials.gov on June 19th. Learn more.
Show more
ClinicalTrials.gov Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...
ClinicalTrials.gov Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more...
ClinicalTrials.gov Menu
Give us feedback

Effect of Ginseng on Glycemic Control

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2013 by St. Michael's Hospital, Toronto.
Recruitment status was:  Active, not recruiting
Sponsor:
Information provided by (Responsible Party):
St. Michael's Hospital, Toronto
ClinicalTrials.gov Identifier:
NCT01841229
First received: April 23, 2013
Last updated: May 22, 2013
Last verified: May 2013
April 23, 2013
May 22, 2013
October 2012
May 2013   (Final data collection date for primary outcome measure)
Glycated hemoglobin (HbA1c) [ Time Frame: 1month ]
HbA1c [ Time Frame: 1month ]
Complete list of historical versions of study NCT01841229 on ClinicalTrials.gov Archive Site
  • Fasting blood glucose [ Time Frame: 1month ]
  • Fasting plasma insulin [ Time Frame: 1 month ]
  • Homeostasis model assessment of insulin resistance (HOMA-IR) [ Time Frame: 1 month ]
fasting glucose, fasting insulin, and the homeostasis model assessment of insulin resistance (HOMA-IR) [ Time Frame: 1 month ]
Not Provided
Not Provided
 
Effect of Ginseng on Glycemic Control
Effect of Ginseng on Glycemic Control: A Systematic Review and Meta-analysis of Controlled Trials to Provide Evidence-based Clinical Recommendations
Ginseng (American ginseng, Asian ginseng, Korean ginseng etc) is expected to show positive hypoglycemic effects, including improvements in glycated blood proteins[HbA1c], fasting glucose, fasting insulin, and the homeostasis model assessment of insulin resistance [HOMA-IR]).
Ginseng has demonstrated to have significant hypoglycemic effect. Its major pharmacological component is considered to be ginsenosides. Several trials have been undertaken in diabetes some of which have demonstrated advantages in glycemic control in both diabetic as well as non diabetic individuals although clinical consistency of results is lacking.The lack of high quality data in this area to support diabetes recommendations represents an urgent call for stronger evidence. A systematic review and meta-analysis of controlled trials remains the "Gold Standard" of evidence for recommendations and clinical guidelines development. Therefore, investigators will conduct a systematic review and meta-analyses of controlled trials to assess the effect of ginseng on glycemic control.
Observational
Not Provided
Not Provided
Not Provided
Probability Sample
Diabetic (type 1 & type 2) Pre-diabetic Hypertensive Healthy
  • Impaired Glucose Tolerance
  • Diabetes
Not Provided
Not Provided
Shishtar E, Sievenpiper JL, Djedovic V, Cozma AI, Ha V, Jayalath VH, Jenkins DJ, Meija SB, de Souza RJ, Jovanovski E, Vuksan V. The effect of ginseng (the genus panax) on glycemic control: a systematic review and meta-analysis of randomized controlled clinical trials. PLoS One. 2014 Sep 29;9(9):e107391. doi: 10.1371/journal.pone.0107391. eCollection 2014. Review.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
770
May 2013
May 2013   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Dietary trials in humans
  • Randomized treatment allocation
  • 1 month
  • Suitable control
  • Viable endpoint data

Exclusion Criteria:

  • Non-human studies
  • Non-randomized treatment allocation
  • <1 month
  • Lack of a suitable control
  • No viable endpoint data
Sexes Eligible for Study: All
Child, Adult, Senior
Yes
Contact information is only displayed when the study is recruiting subjects
Canada
 
 
NCT01841229
MetaG
Yes
Not Provided
Not Provided
St. Michael's Hospital, Toronto
St. Michael's Hospital, Toronto
Not Provided
Principal Investigator: Vladimir Vuksan, PhD St. Michael's Hospital, Toronto
St. Michael's Hospital, Toronto
May 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP