Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade
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ClinicalTrials.gov Identifier: NCT01822132 |
Recruitment Status
:
Completed
First Posted
: April 2, 2013
Last Update Posted
: April 28, 2015
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Sponsor:
Oregon Health and Science University
Collaborator:
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
P. Todd Korthuis, Oregon Health and Science University
Tracking Information | ||||
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First Submitted Date ICMJE | March 21, 2013 | |||
First Posted Date ICMJE | April 2, 2013 | |||
Last Update Posted Date | April 28, 2015 | |||
Study Start Date ICMJE | May 2013 | |||
Actual Primary Completion Date | March 2015 (Final data collection date for primary outcome measure) | |||
Current Primary Outcome Measures ICMJE |
Discounting Tasks [ Time Frame: 28 days ] | |||
Original Primary Outcome Measures ICMJE |
Discounting Tasks [ Time Frame: 28 days ] Delay Discounting economic task that asks subjects to choose between an immediate reward and a second reward that varies in delay until receipt. Probes the neural mechanism of the effect of endogenous opioid blockade on impulsive choice in MA users.
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Change History | Complete list of historical versions of study NCT01822132 on ClinicalTrials.gov Archive Site | |||
Current Secondary Outcome Measures ICMJE |
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Original Secondary Outcome Measures ICMJE |
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Current Other Outcome Measures ICMJE | Not Provided | |||
Original Other Outcome Measures ICMJE | Not Provided | |||
Descriptive Information | ||||
Brief Title ICMJE | Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade | |||
Official Title ICMJE | Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade | |||
Brief Summary | The purpose of this protocol is to learn more about impulsive decision making in people who use methamphetamines. The investigators would like to know if a medication called naltrexone changes how people make decisions. The investigators would also like to know whether changes in decision making can be observed by MRI (magnetic resonance imaging). The research is conducted in Portland, OR. |
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Detailed Description | Not Provided | |||
Study Type ICMJE | Interventional | |||
Study Phase | Not Applicable | |||
Study Design ICMJE | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Investigator) |
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Condition ICMJE |
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Intervention ICMJE |
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Study Arms |
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Publications * | Not Provided | |||
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. |
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Recruitment Information | ||||
Recruitment Status ICMJE | Completed | |||
Actual Enrollment ICMJE |
62 | |||
Original Estimated Enrollment ICMJE |
50 | |||
Actual Study Completion Date | March 2015 | |||
Actual Primary Completion Date | March 2015 (Final data collection date for primary outcome measure) | |||
Eligibility Criteria ICMJE | Summary Inclusion Criteria:
Summary Exclusion Criteria:
The research is conducted in Portland, OR. |
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Sex/Gender |
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Ages | 18 Years to 55 Years (Adult) | |||
Accepts Healthy Volunteers | No | |||
Contacts ICMJE | Contact information is only displayed when the study is recruiting subjects | |||
Listed Location Countries ICMJE | United States | |||
Removed Location Countries | ||||
Administrative Information | ||||
NCT Number ICMJE | NCT01822132 | |||
Other Study ID Numbers ICMJE | ALKIIT-KOR-034 1R21DA033182-01A1 ( U.S. NIH Grant/Contract ) |
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Has Data Monitoring Committee | No | |||
U.S. FDA-regulated Product | Not Provided | |||
IPD Sharing Statement | Not Provided | |||
Responsible Party | P. Todd Korthuis, Oregon Health and Science University | |||
Study Sponsor ICMJE | Oregon Health and Science University | |||
Collaborators ICMJE | National Institute on Drug Abuse (NIDA) | |||
Investigators ICMJE |
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PRS Account | Oregon Health and Science University | |||
Verification Date | April 2015 | |||
ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP |