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Investigation of Anatomical Correlates of Speech Discrimination

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ClinicalTrials.gov Identifier: NCT01781039
Recruitment Status : Recruiting
First Posted : January 31, 2013
Last Update Posted : January 17, 2018
Sponsor:
Information provided by (Responsible Party):

January 29, 2013
January 31, 2013
January 17, 2018
January 2013
January 2020   (Final data collection date for primary outcome measure)
Regression analysis [ Time Frame: February 2014 ]
Regression analysis will be used to look for a correlation between measures of sensory cell and auditory neuron survival and speech recognition performance.
Same as current
Complete list of historical versions of study NCT01781039 on ClinicalTrials.gov Archive Site
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Investigation of Anatomical Correlates of Speech Discrimination
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Understanding speech is essential for good communication. Individuals with hearing loss and poor speech discrimination often have little success with hearing aids because amplifying sound improves audibility, but not clarity of the speech signal. The purpose of this study is to determine the relative importance of the sensory cells of the inner ear and auditory neurons on speech discrimination performance in quiet and in noise. This information may be used as a predictor of hearing aid benefit. The investigators expect to find decreased speech understanding ability resulting from both loss of sensory cells and the loss of auditory neurons.
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Observational
Observational Model: Cohort
Time Perspective: Cross-Sectional
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Non-Probability Sample
Adult patients referred from the St. Elizabeth's Department of Otolaryngology and self-referred patients to the Audiology Clinic.
Sensorineural Hearing Loss
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
100
August 2020
January 2020   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Normal hearing to moderate sensorineural hearing loss
  • Sufficient English proficiency to complete speech discrimination testing in English

Exclusion Criteria:

  • Hearing loss less than a 45 dB HL pure tone average (average hearing thresholds at 500, 1000 and 2000 Hz)
  • Conductive hearing loss
  • Neurodegenerative disease
Sexes Eligible for Study: All
18 Years to 100 Years   (Adult, Senior)
Yes
United States
 
 
NCT01781039
00652
Yes
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Mark Parker, Steward St. Elizabeth's Medical Center of Boston, Inc.
Steward St. Elizabeth's Medical Center of Boston, Inc.
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Principal Investigator: Mark Parker, PhD Steward St. Elizabeth's Medical Center
Steward St. Elizabeth's Medical Center of Boston, Inc.
January 2018