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The Role of Mid-Life Adiposity in Functional Brain Connectivity

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ClinicalTrials.gov Identifier: NCT01777789
Recruitment Status : Terminated (This is a basic research study with no clinical data to report)
First Posted : January 29, 2013
Last Update Posted : February 9, 2016
Sponsor:
Information provided by (Responsible Party):
Medical College of Wisconsin

January 24, 2013
January 29, 2013
February 9, 2016
December 2012
February 2016   (Final data collection date for primary outcome measure)
Brain connectivity measured by fMRI [ Time Frame: One visit ]
Same as current
Complete list of historical versions of study NCT01777789 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
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The Role of Mid-Life Adiposity in Functional Brain Connectivity
The Role of Mid-Life Adiposity in Functional Brain Connectivity
The purpose of the study is to use functional MRI (fMRI) to measure brain connectivity in middle-aged individuals with different levels of body fat. The ultimate goal of this research is to develop an early diagnostic tool for Alzheimer's disease.

Participants will have one visit for:

  • Blood draw
  • Body composition scan
  • Cognitive screen
  • Neurological exam
  • MRI scan

The visit will take approximately 3 hours.

Observational
Observational Model: Case Control
Time Perspective: Cross-Sectional
Not Provided
Retention:   Samples With DNA
Description:
Blood draw
Non-Probability Sample
Healthy volunteers from the community
Alzheimer's Disease
Not Provided
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
60
Same as current
February 2016
February 2016   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • 45-65 years of age
  • Normal memory
  • Right-handed
  • General good physical health

Exclusion Criteria:

  • History of stroke or neurological disease
  • Seizures or head injury with loss of consciousness within the last five years
  • Ferrous (magnetic) or electronic implants (due to the magnet in the MRI scanner)
  • Claustrophobia

More detailed inclusion/exclusion criteria must be met in order to qualify for the study. The study coordinator will determine eligibility.

Sexes Eligible for Study: All
45 Years to 65 Years   (Adult, Older Adult)
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT01777789
PRO16109
No
Not Provided
Not Provided
Medical College of Wisconsin
Medical College of Wisconsin
Not Provided
Principal Investigator: Piero Antuono, MD Medical College of Wisconsin
Medical College of Wisconsin
February 2016