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Difference Between Central and Peripheral Arterial Blood Oxygen Saturation With Different CPB Strategy

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2012 by Xijing Hospital.
Recruitment status was:  Not yet recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01698853
First Posted: October 3, 2012
Last Update Posted: October 3, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Xijing Hospital
September 25, 2012
October 3, 2012
October 3, 2012
October 2012
March 2013   (Final data collection date for primary outcome measure)
The difference between peripheral arterial oxygenation and aortic root blood oxygenation [ Time Frame: patients will be followed up during the cardiopulmonary bypass. Blood samples will be collected at 3 timepoints which is specified in the DESCRIPTION ]
The three time points for blood sample collection are:1.right before clamping the aorta; 2.Three minutes after **** without ventilation;3.5 min after re-initiate mechanical ventilation.
Same as current
No Changes Posted
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Difference Between Central and Peripheral Arterial Blood Oxygen Saturation With Different CPB Strategy
The Difference Between Central and Peripheral Arterial Blood Oxygen Saturation in Patients Undergoing Cardiac Surgery With Different Cardiopulmonary Bypass Strategy

Femoro-femoral cardiopulmonary bypass with retrograde perfusion is needed for totally thoracoscopic cardiac surgery. one of the major complication of retrograde perfusion is organ hypoperfusion.

Arterial blood gas analysis can help to detect hypoperfusion or hypoxia during retrograde perfusion. However,whether the arterial oxygenation status from different parts of the body are the same in the condition of retrograde perfusion have not been studied.

The present study is aimed to determine if there is difference in the arterial oxygenation between peripheral arterial and aortic root during the period of retrograde perfusion.In addition, the impact of artificial ventilation on the difference of arterial oxygenation will also be investigated.

All patients included will be assigned into two different groups according to the surgical approach,one group is named "NP" with normal perfusion,and the other is named "RP" with retrograde perfusion.

For all the patients,we will obtain 0.5ml blood from both peripheral arterial and aortic root for blood gas analysis at some specific time points.

We will focus on the differences of arterial oxygenation between peripheral arterial and aortic root at each group.At the same time,we will analyse the impact of artificial ventilation on it.

Observational
Time Perspective: Prospective
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Non-Probability Sample
patient undergoing totally thoracoscopic cardiac surgery with cardiopulmonary bypass
  • Bypass Complications
  • Disorder of Blood Gas
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
60
May 2013
March 2013   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • age > 18 years old
  • undergoing totally thoracoscopic cardiac surgery with cardiopulmonary bypass

Exclusion Criteria:

  • without informed consent
  • pregnancy
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
China
 
 
NCT01698853
192837
No
Not Provided
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Xijing Hospital
Xijing Hospital
Not Provided
Study Chair: Hailong Dong, Doctor department director
Xijing Hospital
September 2012