Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Effectiveness and Neuropsychological Predictors of Guided Self-Help for Obsessive-Compulsive Disorder (OCD)

This study has been completed.
Information provided by (Responsible Party):
Hartford Hospital Identifier:
First received: August 3, 2012
Last updated: September 4, 2014
Last verified: March 2013

August 3, 2012
September 4, 2014
August 2012
June 2014   (final data collection date for primary outcome measure)
Change in Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) [ Time Frame: Change in Y-BOCS will be assessed over the course of the 17 week treatment trial, then again three months and six months after the treatment. ] [ Designated as safety issue: No ]
The Y-BOCS is a semi-structured interview that assesses severity of obsessions and compulsions.
Same as current
Complete list of historical versions of study NCT01659125 on Archive Site
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Effectiveness and Neuropsychological Predictors of Guided Self-Help for Obsessive-Compulsive Disorder (OCD)
Effectiveness and Neuropsychological Predictors of Guided Self-Help for OCD

The primary aim of this study is to learn about who is most likely to benefit from guided self-help (GSH) for obsessive-compulsive disorder (OCD).

40 Participants with OCD will be recruited. They will be given access to OC Fighter, an internet OCD treatment program. During the 17 week program, participants will meet with a therapist 9 times. Assessments will occur at pretreatment, post-treatment, 3-month follow up and 6-month follow up.

Not Provided
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Obsessive-Compulsive Disorder
Behavioral: "OCFighter"
OCFighter™ s an interactive, internet guided self-help (GSH) treatment program for obsessive-compulsive disorder (OCD). It uses the evidence based approach known as Cognitive Behavioral Therapy (CBT) and was adapted from the previously validated BT STEPS program for OCD. The program teaches the best practice CBT technique to help with OCD called exposure with ritual prevention (ERP).
Other Names:
  • OCFighter
  • Guided Self-help
Experimental: OCFighter
Intervention: Behavioral: "OCFighter"
Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
June 2014
June 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Principal or co-principal diagnosis of OCD
  • Clinical global impression score greater than or equal to 4
  • Y-BOCS score great than or equal to 16
  • Fluency in English
  • Capacity to understand the nature of the study and willingness to sign informed consent form

Exclusion Criteria:

  • Active manic episode, psychosis, pervasive developmental disorder, mental retardation
  • Concurrent OCD psychotherapy
  • Current threat of harm to self or others
  • Previous adequate trial of therapist-administered or self-administered exposure and response prevention for OCD
18 Years to 69 Years
Contact information is only displayed when the study is recruiting subjects
United States
Hartford Hospital
Hartford Hospital
Not Provided
Principal Investigator: Gretchen Diefenbach, Ph.D. Hartford Hospital
Hartford Hospital
March 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP