Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms

Tracking Information
First Submitted Date	May 19, 2012
First Posted Date	May 23, 2012
Last Update Posted Date	April 5, 2018
Study Start Date	November 8, 2005
Primary Completion Date	Not Provided
Current Primary Outcome Measures; (submitted: May 23, 2013)	Marijuana Quit Questionnaire [ Time Frame: 1 to 2 hours ]
Original Primary Outcome Measures	Not Provided
Change History	Complete list of historical versions of study NCT01603992 on ClinicalTrials.gov Archive Site
Current Secondary Outcome Measures; (submitted: May 23, 2013)	Marijuana Craving Questionnaire, and Additional Questions about Marijuana Craving
Original Secondary Outcome Measures	Not Provided
Current Other Outcome Measures	Not Provided
Original Other Outcome Measures	Not Provided
Descriptive Information
Brief Title	Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms
Official Title	Quitting Marijuana Use: Self-Report Study of Quitting Strategies and Withdrawal Symptoms
Brief Summary	Background: - Marijuana is the most widely used illicit drug in the world, yet relatively little is known about users who try to quit without formal treatment ( spontaneous quitting). Studies have suggested that there are some common strategies that many individuals use in spontaneous quitting, such as changing one s lifestyle or identity, reminding oneself of negative consequences, support from family and friends, and religion. However, more research is needed to determine potential treatment strategies for marijuana use. Objectives: To identify strategies used to help with marijuana quitting among non-treatment seeking adult marijuana users.; To identify withdrawal symptoms experienced during marijuana quitting and their relationship to the quitting strategies used and the outcome of the quit attempt.; To evaluate whether subgroups of marijuana users differ in their experience of marijuana quitting. Eligibility: - Individuals at least 18 years of age who have made at least one attempt to quit marijuana use. Design: The study will consist of one visit of approximately 1 to 2 hours.; Participants will fill out three questionnaires. The questionnaires have different types of questions, and will ask about background and lifestyle, marijuana use and craving patterns and behaviors, and difficulties in previous attempts to quit using marijuana.
Detailed Description	Marijuana is the most widely used illicit drug in the world, yet relatively little is known about users who try to quit without formal treatment (so-called spontaneous quitting). This study will use two self-report questionnaires to collect information on the socio-demographic characteristics, marijuana use history, most difficult marijuana quit experience, and marijuana craving from a convenience sample of 1230 adult, non-treatment-seeking marijuana users. The questionnaires take 45-60 minutes to administer. Data will be analyzed for patterns and correlations among the characteristics of the quit attempt, including any withdrawal symptoms, quitting strategies used, and its success. The marijuana craving data will be analyzed to evaluate the validity of this measure of marijuana craving. There are no direct benefits to subjects from study participation. The scientific benefit is an improved understanding of spontaneous quitting of marijuana use, which may lead to improved interventions for marijuana users in the future. There are no physical risks to subjects. There are risks of anxiety or embarrassment while taking the questionnaire and of loss of confidentiality of sensitive information collected about subjects.
Study Type	Observational
Study Design	Not Provided
Target Follow-Up Duration	Not Provided
Biospecimen	Not Provided
Sampling Method	Not Provided
Study Population	Not Provided
Condition	Cannabis Abuse; Cannabis Dependence
Intervention	Not Provided
Study Groups/Cohorts	Not Provided
Publications *	Adamson SJ, Sellman JD. A prototype screening instrument for cannabis use disorder: the Cannabis Use Disorders Identification Test (CUDIT) in an alcohol-dependent clinical sample. Drug Alcohol Rev. 2003 Sep;22(3):309-15.; Boyd SJ, Tashkin DP, Huestis MA, Heishman SJ, Dermand JC, Simmons MS, Gorelick DA. Strategies for quitting among non-treatment-seeking marijuana smokers. Am J Addict. 2005 Jan-Feb;14(1):35-42.; Budney AJ, Hughes JR, Moore BA, Vandrey R. Review of the validity and significance of cannabis withdrawal syndrome. Am J Psychiatry. 2004 Nov;161(11):1967-77. Review.; Koola MM, Boggs DL, Kelly DL, Liu F, Linthicum JA, Turner HE, McMahon RP, Gorelick DA. Relief of cannabis withdrawal symptoms and cannabis quitting strategies in people with schizophrenia. Psychiatry Res. 2013 Oct 30;209(3):273-8. doi: 10.1016/j.psychres.2013.07.044. Epub 2013 Aug 20.; Boggs DL, Kelly DL, Liu F, Linthicum JA, Turner H, Schroeder JR, McMahon RP, Gorelick DA. Cannabis withdrawal in chronic cannabis users with schizophrenia. J Psychiatr Res. 2013 Feb;47(2):240-5. doi: 10.1016/j.jpsychires.2012.10.010. Epub 2012 Nov 10.
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
Recruitment Information
Recruitment Status	Completed
Actual Enrollment; (submitted: April 4, 2018)	822
Original Estimated Enrollment; (submitted: May 19, 2012)	1230
Study Completion Date	May 3, 2012
Primary Completion Date	Not Provided
Eligibility Criteria	INCLUSION CRITERIA: age 18 or older have made at least one attempt to quit marijuana use able to give valid informed consent ability to understand English
Sex/Gender	Sexes Eligible for Study: All
Ages	18 Years and older (Adult, Older Adult)
Accepts Healthy Volunteers	No
Contacts	Contact information is only displayed when the study is recruiting subjects
Listed Location Countries	United States
Removed Location Countries
Administrative Information
NCT Number	NCT01603992
Other Study ID Numbers	999906408; 06-DA-N408
Has Data Monitoring Committee	Not Provided
U.S. FDA-regulated Product	Not Provided
IPD Sharing Statement	Not Provided
Responsible Party	Not Provided
Study Sponsor	National Institute on Drug Abuse (NIDA)
Collaborators	Not Provided
Investigators	Principal Investigator: David A Gorelick, M.D. National Institute on Drug Abuse (NIDA)
PRS Account	National Institutes of Health Clinical Center (CC)
Verification Date	May 3, 2012