Twitter-enabled Mobile Messaging for Smoking Relapse Prevention

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Cornelia Pechmann, University of California, Irvine
ClinicalTrials.gov Identifier:
NCT01602536
First received: May 17, 2012
Last updated: December 4, 2015
Last verified: December 2015

May 17, 2012
December 4, 2015
January 2012
June 2014   (final data collection date for primary outcome measure)
self-reported 7-day point prevalence abstinence from smoking that was sustained at 7, 30 and 60 days after the quit date [ Time Frame: 60 days after quit date ] [ Designated as safety issue: No ]
7-day point prevalence abstinence from smoking at 30 days after the quit date [ Time Frame: 30 days after quit date ] [ Designated as safety issue: No ]
Complete list of historical versions of study NCT01602536 on ClinicalTrials.gov Archive Site
level of engagement based on tweet volume [ Time Frame: 100 days total ] [ Designated as safety issue: No ]
* 7-day point prevalence abstinence from smoking at 7 and 60 days after quit date [ Time Frame: 7 days and 60 days after quit date ] [ Designated as safety issue: No ]
Not Provided
Not Provided
 
Twitter-enabled Mobile Messaging for Smoking Relapse Prevention
Twitter-enabled Mobile Messaging for Smoking Relapse Prevention
In Phase I (N=40), we developed a treatment protocol for smoking cessation and relapse prevention that used virtual quit-smoking Twitter groups and Twitter-enabled interactive peer messaging. We tested and refined this protocol using two quit-smoking Twitter groups. In Phase II (N=160), we conducted a two-arm (test vs. control) randomized controlled trial of the treatment protocol created in Phase I. In Phase III (N=80) we ran additional quit-smoking Twitter groups and tested various interventions to increase engagement in the intervention, e.g., peer leaders. This research provided crucial data about the viability and methodology to be used in a larger randomized controlled trial that would directly measure smoking behavior.

Smoking relapse rates remain high, innovative strategies are needed to lower them, and web-based social networking may help like Twitter. This developmental research examined whether providing virtual (web-based) social support to smokers, through Twitter-enabled interactive peer texting, could help smokers quit and avoid relapses. Twitter is a free social networking and micro-blogging service, one of the most advanced and novel technologies available today that can provide social support to smokers, and it provides free texting to groups. It is global and has many features that are associated with treatment success including interactive, multi-way, live messaging and mobile accessibility, because the messages go instantly to mobile phones and to the web. It can provide an innovative way to reach smokers who might otherwise not seek treatment, and it can be extended to other health domains.

In Phase II which took place from June 2012 through 2013, we conducted a two-condition randomized controlled trial (Aim 2). All participants in this trial (N=160) received 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 1 week of study start. Participants were also randomly assigned at the individual level to one of two conditions: (1) a virtual quit-smoking Twitter group condition where the group members were instructed to use Twitter-enabled interactive peer messaging to help them quit and stay quit, or (2) a control group condition where the group members were not given this instruction or a Twitter group. In total, there were 4 Twitter groups and 4 control groups with 20 smokers randomly assigned to each group (i.e., N=80 test, N=80 control). The primary outcome was self-reported 7-day point prevalence abstinence that was sustained at 7, 30 and 60 days after the quit date. Participants' tweets, their virtual and face-to-face social networks, and several other possible mediating and moderating variables were also analyzed.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Smoking
  • Behavioral: smoking cessation aides
    All participants will receive 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 8 days of study start.
  • Behavioral: Twitter
    Twitter quit-smoking group
  • Experimental: Twitter
    Experimental participants are assigned a 20-person twitter quit-smoking group to interact with, are instructed to use Twitter-enabled interactive peer messaging,and are sent daily messages to encourage interaction. The baseline intervention 'smoking cessation aides' is also provided.
    Interventions:
    • Behavioral: smoking cessation aides
    • Behavioral: Twitter
  • Active Comparator: Control
    Control participants are not assigned to a twitter group. The baseline intervention 'smoking cessation aides' is also provided.
    Intervention: Behavioral: smoking cessation aides
Pechmann C, Pan L, Delucchi K, Lakon CM, Prochaska JJ. Development of a Twitter-based intervention for smoking cessation that encourages high-quality social media interactions via automessages. J Med Internet Res. 2015 Feb 23;17(2):e50. doi: 10.2196/jmir.3772.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
280
June 2014
June 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • must have smoked 100 cigarettes during their lifetime
  • must currently smoke 5 or more cigarettes a day
  • must be in the preparation stage of quitting smoking
  • ages 18-59 years
  • English speaking
  • have a mobile phone with an unlimited texting plan and internet access
  • use text messaging at least once a week
  • use Facebook daily
  • have an active email account
  • live in the continental USA

Exclusion Criteria:

  • a medical condition that is contra-indicated for nicotine replacement therapy:
  • pregnant
  • breast feeding
  • a recent heart attack
  • an irregular heartbeat
  • high blood pressure not controlled with medication
  • skin allergies to adhesive tape or serious skin problems
  • taking a prescription medicine for depression or anxiety
  • use drugs or marijuana regularly
  • live in the same household with another participant
Both
18 Years to 59 Years   (Adult)
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01602536
1R34DA030538-01A1
No
Not Provided
Not Provided
Cornelia Pechmann, University of California, Irvine
University of California, Irvine
Not Provided
Principal Investigator: Cornelia Pechmann, PhD University of California, Irvine
University of California, Irvine
December 2015

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP