Working...
ClinicalTrials.gov
ClinicalTrials.gov Menu

The Parkinson's Genetic Research Study (PaGeR)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01558479
Recruitment Status : Recruiting
First Posted : March 20, 2012
Last Update Posted : October 12, 2018
Sponsor:
Information provided by (Responsible Party):
Cyrus Zabetian, University of Washington

Tracking Information
First Submitted Date March 16, 2012
First Posted Date March 20, 2012
Last Update Posted Date October 12, 2018
Actual Study Start Date September 2009
Estimated Primary Completion Date June 2020   (Final data collection date for primary outcome measure)
Current Primary Outcome Measures Not Provided
Original Primary Outcome Measures Not Provided
Change History Complete list of historical versions of study NCT01558479 on ClinicalTrials.gov Archive Site
Current Secondary Outcome Measures Not Provided
Original Secondary Outcome Measures Not Provided
Current Other Outcome Measures Not Provided
Original Other Outcome Measures Not Provided
 
Descriptive Information
Brief Title The Parkinson's Genetic Research Study
Official Title The Parkinson's Genetic Research Study (PaGeR)
Brief Summary The Parkinson's Genetic Research Study (PaGeR), headed by Dr. Cyrus Zabetian, is searching for genes that increase the risk of developing Parkinson's disease (PD) and related disorders. The study is a joint effort by neurologists and researchers across the United States and is sponsored by the National Institutes of Health. The coordinating center for PaGeR is located at the University of Washington and the VA Puget Sound Health Care System in Seattle.
Detailed Description

PaGeR is focusing on families in which two or more people have been diagnosed with PD. Past research suggests that such "multiplex" families might hold the key to the discovery of new PD genes.

To take part in PaGeR, participants will be asked to complete a questionnaire and to undergo an interview, a neurological exam, a short memory test, and a blood draw. Enrollment in the study usually takes between one and two hours. There is no cost to participate, and all study information is kept strictly confidential.

There are a number of designated sites across the country where families can enroll. However, for family members who are unable to travel to one of these sites, other arrangements can be made.

Study Type Observational
Study Design Observational Model: Family-Based
Time Perspective: Cross-Sectional
Target Follow-Up Duration Not Provided
Biospecimen Retention:   Samples With DNA
Description:
Blood or saliva
Sampling Method Non-Probability Sample
Study Population Families in which two or more people have been diagnosed with Parkinson's disease.
Condition Parkinson's Disease
Intervention Not Provided
Study Groups/Cohorts
  • Case
    Has a diagnosis of Parkinson's disease
  • Control
    No diagnosis of Parkinson's disease
  • Family Member
    Has a family history of Parkinson's disease. Can be affected or unaffected with Parkinson's disease
Publications * Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruitment Information
Recruitment Status Recruiting
Estimated Enrollment
 (submitted: March¬†16,¬†2012)
5000
Original Estimated Enrollment Same as current
Estimated Study Completion Date June 2020
Estimated Primary Completion Date June 2020   (Final data collection date for primary outcome measure)
Eligibility Criteria

Inclusion Criteria:

  • Over 18 years of age
  • Member of a family in which there are two or more living individuals who have been diagnosed with Parkinson's disease

Exclusion Criteria:

  • Under 18 years of age
Sex/Gender
Sexes Eligible for Study: All
Ages 18 Years and older   (Adult, Older Adult)
Accepts Healthy Volunteers Yes
Contacts
Contact: Jennifer Pate 1-855-646-4221
Contact: Krista Specketer (206) 277-5055
Listed Location Countries United States
Removed Location Countries  
 
Administrative Information
NCT Number NCT01558479
Other Study ID Numbers 36777
Has Data Monitoring Committee No
U.S. FDA-regulated Product Not Provided
IPD Sharing Statement Not Provided
Responsible Party Cyrus Zabetian, University of Washington
Study Sponsor University of Washington
Collaborators Not Provided
Investigators
Principal Investigator: Cyrus Zabetian, MD, MS University of Washington, VA Puget Sound Health Care System
PRS Account University of Washington
Verification Date October 2018