Evaluating the Patient-Ventilator Synchrony During Mechanical Ventilation in Patients With Acute Lung Injury

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Chicago
ClinicalTrials.gov Identifier:
NCT01541514
First received: January 17, 2012
Last updated: December 2, 2014
Last verified: December 2014

January 17, 2012
December 2, 2014
July 2011
April 2012   (final data collection date for primary outcome measure)
double stacks [ Time Frame: number per minute over 5 minutes ] [ Designated as safety issue: No ]
ventilator waveform recording
Same as current
Complete list of historical versions of study NCT01541514 on ClinicalTrials.gov Archive Site
  • level of sedation [ Time Frame: baseline ] [ Designated as safety issue: No ]
    Richmond Agitation Sedation Score
  • mode of ventilation [ Time Frame: 30min ] [ Designated as safety issue: No ]
    ventilator adjustment
  • level of sedation [ Time Frame: baseline ] [ Designated as safety issue: No ]
    Richmond Agition Sedation Score
  • mode of ventilation [ Time Frame: 30min ] [ Designated as safety issue: No ]
    ventilator adjustment
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Evaluating the Patient-Ventilator Synchrony During Mechanical Ventilation in Patients With Acute Lung Injury
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The overall purpose to the study is to prospectively study how often patients with and without acute lung injury (ALI) have patient-ventilator asynchrony demonstrated as stacked breaths. The investigators seek to describe the quantity of stacked breaths by continuously recording flow, volume, and pressure waveforms routinely displayed on the vent. The investigators also seek to describe how primary ICU teams manage asynchrony documenting interventions of sedation or vent manipulation and what modality is most successful.
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Observational
Observational Model: Cohort
Time Perspective: Prospective
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Probability Sample
adult ICU patients receiving mechanical ventilation
Mechanically Ventilated ICU Patients
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
30
December 2013
April 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

age > 18 years intubated and mechanically ventilated diagnosed with acute lung injury (ALI) or requiring mechanical ventilation for reasons other than ALI

Exclusion Criteria:

neurological deficits (acute or chronic) that prevent effective diaphragm activity.

  • Neuromuscular disease affecting the diaphragm
  • Neuromuscular blockade
Both
18 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01541514
11-0172
No
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University of Chicago
University of Chicago
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Principal Investigator: Jesse Hall, MD University of Chicago
University of Chicago
December 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP