Action Against Malnutrition Through Agriculture (AAMA) Plus MNP Study (MNP)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01488305
Recruitment Status : Unknown
Verified December 2011 by Pooja Pandey Rana, Helen Keller International.
Recruitment status was:  Active, not recruiting
First Posted : December 8, 2011
Last Update Posted : December 8, 2011
University of California, Davis
Information provided by (Responsible Party):
Pooja Pandey Rana, Helen Keller International

December 5, 2011
December 8, 2011
December 8, 2011
October 2010
February 2012   (Final data collection date for primary outcome measure)
Anemia [ Time Frame: One year ]
All three arms anemia status will be compared after one year of MNP distribution (assess the additional value of MNP)
Same as current
No Changes Posted
Impact on growth of children [ Time Frame: one year ]
Assess the growth of children (wasting, underweigh and stunting)after one year of MNP distribution (MNP distribution started in March 2011)
Same as current
Not Provided
Not Provided
Action Against Malnutrition Through Agriculture (AAMA) Plus MNP Study
Impact of Micronutrient Powders (MNP)With Homestead Food Production and an Intensive Community Level IYCF-BCC Intervention on Reducing Anemia and Improving Growth in Young Children, Nepal
Helen Keller International (HKI), the ministry of health and population, and ministry of agriculture and cooperatives, of Nepal and local non-governmental organizations (NGO) partners are currently implementing a USAID funded Action Against Malnutrition Through Agriculture (AAMA) project in Baitadi district located in far Western development region of Nepal. HKI is undertaking this study within the AAMA project to test whether providing micro-nutrient powders (MNPs) in a programmatic context along with homestead food production (HFP) and an intensive community level Infant and Young Child Feeding Behavior change communication (IYCF-BCC) intervention will have a greater impact on reducing anemia and improving growth in young children than only providing the HFP and IYCF-BCC intervention without MNPs or a control with no intervention.

The AAMA project uses the homestead food production (HFP) model that focuses on increasing households year round access to nutritious food as a platform to deliver a proven essential nutrition actions (ENA) related messages to household with children less than 2 years old. The AAMA project seeks to examine the effects of household level HFP on malnutrition. So the recipient and other partners wishes to undertake a study to explore a plausible delivery mechanism for MNPs along with HFP and intensive community level IYCF-BCC and their impact on infant/child growth and anemia.

The study is a cluster randomized controlled trial with a three arm factorial design. The trial involve 330 randomly selected children aged 6-9 months at the time of enrollment (n=110 per each of the three study arms). MNPs distributed through FCHVs to 110 children selected from communities that already have the HFP and IYCF-BCC intervention. This group of children will be compared on outcome parameters for anemia, growth (stunting, underweight and wasting) and infections (diarrhea, fever and cough) to a similar sub-set of children (n=110) who receive only the HFP and IYCF-BCC intervention and to a third sub-set of control children of similar age (n=110) who are not receiving either of these interventions. Children aged 6-9 months were chosen for the study because this age range captures the recommended age for introduction of complementary foods to children and our chosen age group also falls within the 0-24 month age range which is considered the period of rapid growth and development and therefore period of highest nutrient requirements in children.

Not Applicable
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Dietary Supplement: MNP (micro-nutrient powders)
MNP is added to explore the additional value of MNP in existing AAMA program
Other Name: MNP sub study in AAMA
  • No Intervention: Only government regular program
    One arm is control arm, in this arm no additional program is added in government regular program
  • No Intervention: AAMA arm (HFP and IYCF BCC)
    Second arm is AAMA project intervention which includes HFP activities, ENA and BCC activities
  • No Intervention: MNP added in AAMA
    It is actually a intervention arm
    Intervention: Dietary Supplement: MNP (micro-nutrient powders)
Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Unknown status
Same as current
March 2012
February 2012   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Children 6-9 months of age during enrollment time
  • Mothers who want to enroll their children in study

Exclusion Criteria:

  • Severe anemia
  • Children age below six months and age over 23 months during study time
Sexes Eligible for Study: All
6 Months to 23 Months   (Child)
Contact information is only displayed when the study is recruiting subjects
09-000076- AT
MNP impact study ( Other Grant/Funding Number: 09-000076-AT10 )
Not Provided
Not Provided
Pooja Pandey Rana, Helen Keller International
Helen Keller International
University of California, Davis
Principal Investigator: Pooja Pandey Rana, MPH Helen Keller International
Helen Keller International
December 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP