We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study (BIG3)

This study is enrolling participants by invitation only.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01460264
First Posted: October 26, 2011
Last Update Posted: April 20, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Region Skane
October 25, 2011
October 26, 2011
April 20, 2017
October 16, 2013
December 2020   (Final data collection date for primary outcome measure)
Not Provided
Not Provided
Complete list of historical versions of study NCT01460264 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study
BIG3 - An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study
This is an observational study aiming to identify and validate biomarkers (including imaging and clinical descriptors) for chronic obstructive pulmonary disease (COPD), cardiovascular disease (CVD) and lung cancer.
Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:
whole blood, serum
Non-Probability Sample
Community sample,residents in Skåne county Sweden.
  • Chronic Obstructive Pulmonary Disease
  • Cardiovascular Diseases
  • Lung Cancer
Not Provided
  • exposed
    current daily smokers 100 cigarettes or more during lifetime
  • unexposed
    current non-smokers
Gerhardsson de Verdier M. The big three concept: a way to tackle the health care crisis? Proc Am Thorac Soc. 2008 Dec 1;5(8):800-5. doi: 10.1513/pats.200806-058TH.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Enrolling by invitation
10000
December 2020
December 2020   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • 45-75 years
Sexes Eligible for Study: All
45 Years to 75 Years   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Sweden
 
 
NCT01460264
BIG3-Region_Skane
No
Not Provided
Not Provided
Region Skane
Region Skane
Not Provided
Study Chair: Ulf Malmqvist, MD, PhD Skane University Hospital
Principal Investigator: David Erlinge, MD, PhD Skane University Hospital
Principal Investigator: Claes-Göran Löfdahl, MD, PhD Skane University Hospital
Principal Investigator: Maria Planck, MD, PhD Skane University Hospital
Region Skane
April 2017