The Relationship Between Allergic Rhinitis and Geographic Tongue (AR-GT)

• ClinicalTrials.gov Identifier: NCT01454492
• Recruitment Status: Unknown
• First Posted: October 19, 2011
• Last Update Posted: October 19, 2011
• Sponsor: China Medical University Hospital
• Information provided by (Responsible Party): China Medical University Hospital

Tracking Information

• First Submitted Date: October 4, 2011
• First Posted Date: October 19, 2011
• Last Update Posted Date: October 19, 2011
• Study Start Date: September 2011
• Estimated Primary Completion Date: March 2012 (Final data collection date for primary outcome measure)
• Current Primary Outcome Measures (submitted: October 18, 2011): Number of participants with Adverse Events [ Time Frame: 8th month ]
• Original Primary Outcome Measures: Same as current
• Change History: No Changes Posted
• Current Secondary Outcome Measures: Not Provided
• Original Secondary Outcome Measures: Not Provided
• Current Other Pre-specified Outcome Measures: Not Provided
• Original Other Pre-specified Outcome Measures: Not Provided

Descriptive Information

• Brief Title: The Relationship Between Allergic Rhinitis and Geographic Tongue
• Official Title: Not Provided

Brief Summary

Allergic rhinitis is a complex chronic inflammatory disease, it always presents with nasal obstruction, nasal itching, sneezing and runny nose. Whether in adults or children, rhinitis is a complex disease. The prevalence of allergic rhinitis in Taiwan is about 24-29%. Taiwan is a developing country. It is a hot and humid country. In developing countries, industrialization, air pollution makes the constantly increasing number of patients with rhinitis. Penghu in 1994 for children aged 7 to 14 by the study found that among 7599 people, 1766 people have allergic rhinitis, about 23.2%. Allergic rhinitis is a complex chronic disease. So, it become a diagnostic challenge, its prevalence always underestimated. The prevalence of rhinitis has increased in recent years. The phenomenon of underestimate is caused by variety of personal and environmental factors. Allergic rhinitis had increased direct and indirect social and economic burden.

Geographic tongue is a benign tongue performance. Geographic tongue has been reported their relevance to allergy. Geographic tongue is a chronic tongue situation. The causes of geographic tongue still remains unknown. Allergic rhinitis is a diagnostic challenge to clinicians. The investigators hope that geographic tongue could play a role in the diagnostic of allergic rhinitis. The prevalence of geographic tongue in the United States is about 1.8%, white Americans and Mexicans have a higher incidence rate. This study will investigate the relevance between allergic rhinitis and geographic tongue. The investigators will analyze the relevant gender, age, severity of inspection reports. The research results wound provide an important reference to the diagnosis of allergic rhinitis.

• Detailed Description: Not Provided
• Study Type: Observational
• Study Design: Observational Model: Case-Control; Time Perspective: Prospective
• Target Follow-Up Duration: Not Provided
• Biospecimen: Not Provided
• Sampling Method: Non-Probability Sample
• Study Population: Group 1: Allergy rhinitis Group 2: Non-allergy rhinitis

Condition

• Allergic Rhinitis
• Geographic Tongue

• Intervention: Not Provided

Study Groups/Cohorts

• Allergy rhinitis
  Allergy rhinitis patients group
• Non- Allergy rhinitis
  Non- Allergy rhinitis patients group

Publications *

• Miloglu O, Goregen M, Akgul HM, Acemoglu H. The prevalence and risk factors associated with benign migratory glossitis lesions in 7619 Turkish dental outpatients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Feb;107(2):e29-33. doi: 10.1016/j.tripleo.2008.10.015.
• Reamy BV, Derby R, Bunt CW. Common tongue conditions in primary care. Am Fam Physician. 2010 Mar 1;81(5):627-34.
• Masferrer E, Jucgla A. Images in clinical medicine. Geographic tongue. N Engl J Med. 2009 Nov 12;361(20):e44. doi: 10.1056/NEJMicm0810145. No abstract available.
• Shulman JD, Carpenter WM. Prevalence and risk factors associated with geographic tongue among US adults. Oral Dis. 2006 Jul;12(4):381-6. doi: 10.1111/j.1601-0825.2005.01208.x.
• Ugar-Cankal D, Denizci S, Hocaoglu T. Prevalence of tongue lesions among Turkish schoolchildren. Saudi Med J. 2005 Dec;26(12):1962-7.

Recruitment Information

• Recruitment Status: Unknown status
• Estimated Enrollment (submitted: October 18, 2011): 300
• Original Estimated Enrollment: Same as current
• Estimated Study Completion Date: September 2012
• Estimated Primary Completion Date: March 2012 (Final data collection date for primary outcome measure)

Eligibility Criteria

Inclusion Criteria:

• rhinitis and non-rhinitis patients
• willing to complete the study
• no limitation of tongue movement

Exclusion Criteria:

• more than 90 years old or younger than 20 years old
• unable to complete the study

Sex/Gender

• Sexes Eligible for Study: All

• Ages: 20 Years to 89 Years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Contacts: Contact information is only displayed when the study is recruiting subjects
• Listed Location Countries: Taiwan

Administrative Information

• NCT Number: NCT01454492
• Other Study ID Numbers: CMUH-3485
• Has Data Monitoring Committee: Yes
• U.S. FDA-regulated Product: Not Provided
• IPD Sharing Statement: Not Provided
• Current Responsible Party: China Medical University Hospital
• Original Responsible Party: Same as current
• Current Study Sponsor: China Medical University Hospital
• Original Study Sponsor: Same as current
• Collaborators: Not Provided

Investigators

• Principal Investigator: CJ Tai, M.D.; China Medical University Hospital

• PRS Account: China Medical University Hospital
• Verification Date: October 2011