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IMproved PREdiction of Severe Sepsis in the Emergency Department (IMPRESSED)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Axis Shield Diagnostics Ltd
ClinicalTrials.gov Identifier:
NCT01392508
First received: July 11, 2011
Last updated: April 13, 2017
Last verified: April 2017
July 11, 2011
April 13, 2017
March 2011
September 2015   (Final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT01392508 on ClinicalTrials.gov Archive Site
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IMproved PREdiction of Severe Sepsis in the Emergency Department
Prospective, Non-interventional, Multi-centre Clinical Study to Assess the Clinical Validity of the Heparin Binding Protein (HBP) Assay for Indicating the Presence, or Outcome, of Severe Sepsis (Including Septic Shock), Over 72 Hours, in Patients With Suspected Infection Following Emergency Department Admission.
The purposes of this study is to determine whether Heparin Binding Protein (HBP) can be used as a marker of severe sepsis (including septic shock) in patients presenting to the emergency department with suspected infection.
Not Provided
Observational
Observational Model: Case-Only
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:
Plasma (LiHep and citrate)
Probability Sample
Patients presenting to emergency department with suspected infection
  • Systemic Inflammatory Response Syndrome (SIRS)
  • Sepsis
  • Severe Sepsis
  • Septic Shock
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Linder A, Arnold R, Boyd JH, Zindovic M, Zindovic I, Lange A, Paulsson M, Nyberg P, Russell JA, Pritchard D, Christensson B, Åkesson P. Heparin-Binding Protein Measurement Improves the Prediction of Severe Infection With Organ Dysfunction in the Emergency Department. Crit Care Med. 2015 Nov;43(11):2378-86. doi: 10.1097/CCM.0000000000001265.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
759
September 2015
September 2015   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Greater than or equal to 18 years
  • Suspected Infection
  • one or more SIRS criteria
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Sweden,   United States
 
 
NCT01392508
PEP-FMHBP-001
No
Not Provided
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Axis Shield Diagnostics Ltd
Axis Shield Diagnostics Ltd
Not Provided
Principal Investigator: Adam Linder Skanes Universitetssjukhus I Lund, Sweden
Principal Investigator: Magnus Paulsson Skanes universitetssjukhuset i Malmo
Principal Investigator: Patrik Nyberg Universitetssjukhuset i Linkoping
Principal Investigator: Anna Lange-Jendeberg Universitetssjukhuset i Orebro
Principal Investigator: Ryan Arnold The Cooper Health System
Axis Shield Diagnostics Ltd
April 2017

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP