Biomarker in Tissue Samples From Patients With Ewing Sarcoma
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ClinicalTrials.gov Identifier: NCT01365949 |
Recruitment Status
:
Completed
First Posted
: June 3, 2011
Last Update Posted
: July 11, 2016
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Sponsor:
Children's Oncology Group
Collaborator:
National Cancer Institute (NCI)
Information provided by (Responsible Party):
Children's Oncology Group
Tracking Information | ||||
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First Submitted Date | June 1, 2011 | |||
First Posted Date | June 3, 2011 | |||
Last Update Posted Date | July 11, 2016 | |||
Study Start Date | May 2011 | |||
Actual Primary Completion Date | July 2016 (Final data collection date for primary outcome measure) | |||
Current Primary Outcome Measures |
Frequency of INI1 protein loss in Ewing Sarcoma | |||
Original Primary Outcome Measures | Same as current | |||
Change History | Complete list of historical versions of study NCT01365949 on ClinicalTrials.gov Archive Site | |||
Current Secondary Outcome Measures | Not Provided | |||
Original Secondary Outcome Measures | Not Provided | |||
Current Other Outcome Measures | Not Provided | |||
Original Other Outcome Measures | Not Provided | |||
Descriptive Information | ||||
Brief Title | Biomarker in Tissue Samples From Patients With Ewing Sarcoma | |||
Official Title | INI-1 Deletions in Ewing Sarcoma | |||
Brief Summary | RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research trial studies biomarkers in tissue samples from patients with Ewing sarcoma. |
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Detailed Description | OBJECTIVES:
OUTLINE: Previously collected tissue samples are analyzed for INI-1 protein loss by IHC and tissue microarray. |
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Study Type | Observational | |||
Study Design | Observational Model: Case-Only Time Perspective: Retrospective |
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Target Follow-Up Duration | Not Provided | |||
Biospecimen | Retention: Samples With DNA Description: Tissue |
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Sampling Method | Non-Probability Sample | |||
Study Population | Diagnosis of Ewing sarcoma. | |||
Condition | Sarcoma | |||
Intervention |
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Study Groups/Cohorts | Not Provided | |||
Publications * | Not Provided | |||
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. |
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Recruitment Information | ||||
Recruitment Status | Completed | |||
Estimated Enrollment |
40 | |||
Original Estimated Enrollment | Same as current | |||
Study Completion Date | Not Provided | |||
Actual Primary Completion Date | July 2016 (Final data collection date for primary outcome measure) | |||
Eligibility Criteria | DISEASE CHARACTERISTICS:
PATIENT CHARACTERISTICS:
PRIOR CONCURRENT THERAPY:
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Sex/Gender |
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Ages | up to 120 Years (Child, Adult, Senior) | |||
Accepts Healthy Volunteers | No | |||
Contacts | Contact information is only displayed when the study is recruiting subjects | |||
Listed Location Countries | Not Provided | |||
Removed Location Countries | ||||
Administrative Information | ||||
NCT Number | NCT01365949 | |||
Other Study ID Numbers | AEWS11B1 COG-AEWS11B1 ( Other Identifier: Children's Oncology Group ) NCI-2011-02857 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) ) AEWS11B1 ( Other Identifier: Children's Oncology Group ) |
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Has Data Monitoring Committee | No | |||
U.S. FDA-regulated Product | Not Provided | |||
IPD Sharing Statement | Not Provided | |||
Responsible Party | Children's Oncology Group | |||
Study Sponsor | Children's Oncology Group | |||
Collaborators | National Cancer Institute (NCI) | |||
Investigators |
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PRS Account | Children's Oncology Group | |||
Verification Date | July 2016 |