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Impact of Dissection Area on the Clinical Outcome of Endoscopic Thyroidectomy (ET)

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ClinicalTrials.gov Identifier: NCT01338597
Recruitment Status : Unknown
Verified April 2011 by Second Military Medical University.
Recruitment status was:  Not yet recruiting
First Posted : April 19, 2011
Last Update Posted : April 19, 2011
Information provided by:

April 11, 2011
April 19, 2011
April 19, 2011
April 2011
December 2011   (Final data collection date for primary outcome measure)
post-operative pain [ Time Frame: 24h post-operation ]
24hs after operation, post-operative pain is evaluated by VAS(visual analoge scale)
Same as current
No Changes Posted
number of patients with adverse effect [ Time Frame: within 3 months after surgery ]
record how many patients had adverse effects(eg. bruise, seroma, hematoma, hoarseness,hypocalciemia)
Same as current
Not Provided
Not Provided
Impact of Dissection Area on the Clinical Outcome of Endoscopic Thyroidectomy
Clinical Benefits of Reduced Subcutaneous Dissection in Endoscopic Thyroidectomy
The purpose of this study is to investigate whether reduced subcutaneous dissection area could offer patients more clinical benefits.
To create a working place in the chest wall is an inevitable step of endoscopic thyroidectomy. Large subcutaneous area was considered a drawback of endoscopic thyroidectomy. The purpose of this study is to investigate whether subcutaneous dissection area has influence on clinical outcome of endoscopic thyroidectomy, such as post-operative pain, complication rate and post-operative discomfort.
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Thyroid Tumor
Procedure: endoscopic thyroidectomy
endoscopic thyroidectomy via the breast approach. the difference between two arms is in the subcutaneous dissection area.
Other Name: limited flap dissection endoscopic thyroidectomy
  • Experimental: standard
    3 trocars are needed. two in the circumareolar region and one in the parasternal region. the dissection area begins from the trocar site and extends to the neck.
    Intervention: Procedure: endoscopic thyroidectomy
  • Experimental: limited dissection
    the dissection is reduced by creating a long tunnel from the trocar site and the dissection area confined in the upper chest wall and in the neck.
    Intervention: Procedure: endoscopic thyroidectomy
Wang M, Zhang T, Mao Z, Dong F, Li J, Lu A, Hu W, Zang L, Jiang Y, Zheng M. Effect of endoscopic thyroidectomy via anterior chest wall approach on treatment of benign thyroid tumors. J Laparoendosc Adv Surg Tech A. 2009 Apr;19(2):149-52. doi: 10.1089/lap.2008.0296.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
Unknown status
June 2012
December 2011   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • thyroid nodule diagnosed by ultrasound
  • willing to undergo endoscopic thyroidectomy

Exclusion Criteria:

  • conversion to open surgery
  • unwilling to join the research
Sexes Eligible for Study: All
18 Years to 50 Years   (Adult)
Contact information is only displayed when the study is recruiting subjects
Not Provided
Not Provided
department of general surgery, changzheng hospital
Second Military Medical University
Not Provided
Study Chair: ming qiu, MD Changzheng Hospital
Second Military Medical University
April 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP