Now Available: Final Rule for FDAAA 801 and NIH Policy on Clinical Trial Reporting

Frequency and Origin of Dysnatremias in the Emergency Department

This study has been withdrawn prior to enrollment.
(Job change of responsible investigators)
Sponsor:
Collaborator:
Steering committee of the NCCR
Information provided by:
University Hospital Inselspital, Berne
ClinicalTrials.gov Identifier:
NCT01326429
First received: March 29, 2011
Last updated: July 22, 2015
Last verified: July 2015

March 29, 2011
July 22, 2015
October 2011
March 2013   (final data collection date for primary outcome measure)
Frequency of hypo- and hypernatremia in the emergency department [ Time Frame: approx. 6 months ] [ Designated as safety issue: No ]
The investigators aim to determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital.
Frequency of hypo- and hypernatremia in the emergency department [ Time Frame: approx. 6 months ] [ Designated as safety issue: No ]
We aim to determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital.
Complete list of historical versions of study NCT01326429 on ClinicalTrials.gov Archive Site
Origin of hypo- and hypernatremia in the emergency department [ Time Frame: approx. 6 months ] [ Designated as safety issue: No ]
The investigators try to investigate the mechanisms leading to the development of hypo- and hypernatremia in patients admitted to the emergency department.
Origin of hypo- and hypernatremia in the emergency department [ Time Frame: approx. 6 months ] [ Designated as safety issue: No ]
We try to investiagte the mechanisms leading to the development of hypo- and hypernatremia in patients admitted to the emergency department.
Not Provided
Not Provided
 
Frequency and Origin of Dysnatremias in the Emergency Department
Frequency and Origin of Dysnatremias in the Emergency Department

Hypo- and hypernatremia are the most frequent electrolyte disorders found in hospitalized patients. The increasing use of diuretics and other medications influencing the water and sodium homeostasis potentially lead to a rise in the prevalence of the electrolyte disorders. Only little data is available on the frequency and the mechanisms leading to hypo-/hypernatremia.

Thus, the investigators aim to A.) determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital and B.) explore the mechanisms leading to the development of dysnatremias by detailed clinical and laboratory examinations.

Not Provided
Observational
Observational Model: Case-Only
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:
whole blood
Non-Probability Sample
All patients admitted to the emergency department of a large tertiary university hospital with a serum sodium below 135 mmol/L (hyponatremia) or exceeding 145 mmol/L.
  • Hyponatremia
  • Hypernatremia
Not Provided
  • Hypernatremia
    Patients admitted to the emergency department with a serum sodium exceeding 145 mmol/L.
  • Hyponatremia
    Patients admitted to the emergency room with a serum sodium below 135 mmol/L.
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Withdrawn
0
March 2013
March 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Serum sodium below 135 mmol/L (i.e. hyponatremia); serum sodium exceeding 145 mmol/L (hypernatremia)

Exclusion Criteria:

  • Patients below age 18 years; patients declining study participation.
Both
18 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Not Provided
Switzerland
 
NCT01326429
KEK 019/11
No
Not Provided
Not Provided
Gregor Lindner M.D., Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern
University Hospital Inselspital, Berne
Steering committee of the NCCR
Principal Investigator: Gregor Lindner, M.D. Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern
Study Chair: Felix J Frey, M.D. Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern
University Hospital Inselspital, Berne
July 2015

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP