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Natural History of Mineral Metabolism Parameters and Protein-bound Toxins in Incident Peritoneal Dialysis Patients

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ClinicalTrials.gov Identifier: NCT01306149
Recruitment Status : Completed
First Posted : March 1, 2011
Last Update Posted : October 25, 2017
Sponsor:
Information provided by (Responsible Party):
Björn Meijers, Universitaire Ziekenhuizen Leuven

February 23, 2011
March 1, 2011
October 25, 2017
July 2002
January 31, 2017   (Final data collection date for primary outcome measure)
natural history of clearances and serum parameters of mineral metabolism and protein-bound toxins [ Time Frame: 15 years ]
To evaluate the natural history of plasma concentrations and renal and peritoneal clearances of small water-soluble uremic retention molecules (URM), 'middle molecules, and protein bound URM in incident peritoneal dialysis (PD) patients.
Same as current
Complete list of historical versions of study NCT01306149 on ClinicalTrials.gov Archive Site
determinants of generation rate of uremic retention solutes [ Time Frame: 15 years on average ]
To evaluate the natural history and determinants of the generation rate of URM originating from bacterial protein fermentation in PD patients.
determinants of generation rate of uremic retention solutes [ Time Frame: 15 years ]
To evaluate the natural history and determinants of the generation rate of URM originating from bacterial protein fermentation in PD patients.
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Not Provided
 
Natural History of Mineral Metabolism Parameters and Protein-bound Toxins in Incident Peritoneal Dialysis Patients
Natural History of Biochemical Parameters of Mineral Metabolism and Protein-bound Uremic Retention Molecules in Incident Peritoneal Dialysis Patients: a Longitudinal Observational Study

The aims of this study are

  1. To evaluate the natural history of plasma concentrations and renal and peritoneal clearances of small water-soluble uremic retention molecules (URM), 'middle molecules', and protein bound URM in incident peritoneal dialysis (PD) patients.
  2. To evaluate the natural history and determinants of the generation rate of URM originating from bacterial protein fermentation in PD patients.
  3. To evaluate the natural history of biochemical parameters of mineral metabolism in incident PD patients.
Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:
whole blood, serum, urine and dialysate
Non-Probability Sample
Incident peritoneal dialysis patients
Complication of Peritoneal Dialysis
Not Provided
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
96
250
January 31, 2017
January 31, 2017   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Incident PD patients, defined as patients who started on PD as first renal replacement therapy less than 8 weeks before inclusion
  • written informed consent
  • age > 18 years old
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Belgium
 
 
NCT01306149
FWO01-03-21
No
Not Provided
Not Provided
Björn Meijers, Universitaire Ziekenhuizen Leuven
Universitaire Ziekenhuizen Leuven
Not Provided
Principal Investigator: Pieter Evenepoel, MD,PhD University Hospital, Leuven, Belgium
Universitaire Ziekenhuizen Leuven
October 2017