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Lymphoma in the Orbit

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ClinicalTrials.gov Identifier: NCT01302912
Recruitment Status : Unknown
Verified November 2011 by University of Zurich.
Recruitment status was:  Enrolling by invitation
First Posted : February 24, 2011
Last Update Posted : November 4, 2011
Sponsor:
Information provided by (Responsible Party):
University of Zurich

Tracking Information
First Submitted Date February 23, 2011
First Posted Date February 24, 2011
Last Update Posted Date November 4, 2011
Study Start Date February 2011
Primary Completion Date Not Provided
Current Primary Outcome Measures Not Provided
Original Primary Outcome Measures Not Provided
Change History
Current Secondary Outcome Measures Not Provided
Original Secondary Outcome Measures Not Provided
Current Other Pre-specified Outcome Measures Not Provided
Original Other Pre-specified Outcome Measures Not Provided
 
Descriptive Information
Brief Title Lymphoma in the Orbit
Official Title Not Provided
Brief Summary

Imaging techniques have considerably improved over the last decades and ocular adnexal lymphomas (OALs) nowadays can be detected. As major advances in immunophenotyping and molecular diagnostics in histology have been achieved offering an accurate diagnosis, the investigators would like to introduce that surgical biopsy of an orbital lymphoma becomes crucial for the possibility of a correct diagnosis and proper treatment. As radiotherapy accomplished great preciseness as well and OALs respond excellently to radiation, this therapy should be the treatment of choice in local defined lymphomas instead of blind treatment with steroids. Radiation results in great local control rates of 85% to 100%

  • Trial with surgical intervention
Detailed Description Not Provided
Study Type Observational
Study Design Observational Model: Cohort
Time Perspective: Retrospective
Target Follow-Up Duration Not Provided
Biospecimen Not Provided
Sampling Method Non-Probability Sample
Study Population Patient, who underwent biopsy of an ocular adnexal lymphoma between 01/2006 and 12/2010 at the University Hospital Zurich, Division of Ophthalmology
Condition Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma
Intervention Procedure: Lymphoma-Biopsy
Patients after biopsy of orbital lymphoma
Study Groups/Cohorts Not Provided
Publications * Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruitment Information
Recruitment Status Unknown status
Estimated Enrollment
 (submitted: February¬†23,¬†2011)
50
Original Estimated Enrollment Same as current
Estimated Study Completion Date May 2012
Primary Completion Date Not Provided
Eligibility Criteria

Inclusion criteria: - both genders

  • >17 years of age
  • underwent biopsy of an ocular adnexal lymphoma between 01/2006 and 12/2010 at the University Hospital Zurich, Division of Ophthalmology
  • diagnosis histologically proven

Exclusion criteria:

  • less than 18 years of age
  • patient underwent no MRI before surgery (biopsy)
Sex/Gender
Sexes Eligible for Study: All
Ages 18 Years and older   (Adult, Older Adult)
Accepts Healthy Volunteers No
Contacts Contact information is only displayed when the study is recruiting subjects
Listed Location Countries Switzerland
Removed Location Countries  
 
Administrative Information
NCT Number NCT01302912
Other Study ID Numbers USZ-OALs-Register
Has Data Monitoring Committee Not Provided
U.S. FDA-regulated Product Not Provided
IPD Sharing Statement Not Provided
Responsible Party University of Zurich
Study Sponsor University of Zurich
Collaborators Not Provided
Investigators
Principal Investigator: Karla Chaloupka, MD University Hospital Zurich, Ophtalmic Clinic
PRS Account University of Zurich
Verification Date November 2011