We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov Menu

Endometrial Biopsy Protocol for In Vitro Fertilization (IVF)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01278706
Recruitment Status : Unknown
Verified December 2010 by Kaplan Medical Center.
Recruitment status was:  Not yet recruiting
First Posted : January 19, 2011
Last Update Posted : January 26, 2011
Information provided by:

January 18, 2011
January 19, 2011
January 26, 2011
January 2011
January 2013   (Final data collection date for primary outcome measure)
pregnancy rates [ Time Frame: 2 years ]
Same as current
Complete list of historical versions of study NCT01278706 on ClinicalTrials.gov Archive Site
live birth rates [ Time Frame: 3 years ]
Same as current
Not Provided
Not Provided
Endometrial Biopsy Protocol for In Vitro Fertilization (IVF)
Comparing Timing and Number of Endometrial Biopsies in IVF Treatment and Identifying Biochemical Markers to Predict Endometrial Receptivity

Endometrial biopsy has been shown to improve IVF pregnancy and live birth rates. The optimal time of performing the biopsy is yet to be established.

In this study, the investigators will compare different temporal timing of the biopsies with regards to the menstrual cycle and their affect on the success rates of the treatment.

Not Provided
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
  • Infertility
  • Recurrent Implantation Failure
Procedure: endometrial biopsy/ies
performing office endometrial biopsy with a disposable sterile catheter
  • No Intervention: no treatment
  • Experimental: one biopsy, proliferative phase
    Intervention: Procedure: endometrial biopsy/ies
  • Experimental: one biopsy, secretory phase
    Intervention: Procedure: endometrial biopsy/ies
  • Experimental: two biopsies
    Intervention: Procedure: endometrial biopsy/ies
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
Unknown status
Not Provided
January 2013   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • normal menstrual cycle
  • between 1-6 previous failed IVF cycles
  • normal hormonal profile

Exclusion Criteria:

  • intrauterine procedure in last 3 months
  • hydrosalpinx
  • intrauterine lesion /malformation
Sexes Eligible for Study: Female
18 Years to 38 Years   (Adult)
Contact information is only displayed when the study is recruiting subjects
Not Provided
Not Provided
Amihai Barash M.D. IVF Unit Director, Kaplan Medical Center
Kaplan Medical Center
Not Provided
Not Provided
Kaplan Medical Center
December 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP