Now Available: Final Rule for FDAAA 801 and NIH Policy on Clinical Trial Reporting

Attenuation of Pain in Men and Women

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified October 2010 by University of Wisconsin, Madison.
Recruitment status was:  Recruiting
Sponsor:
Information provided by:
University of Wisconsin, Madison
ClinicalTrials.gov Identifier:
NCT01220414
First received: September 28, 2010
Last updated: October 15, 2010
Last verified: October 2010

September 28, 2010
October 15, 2010
September 2010
January 2012   (final data collection date for primary outcome measure)
Pain threshold, pain ratings, and temporal summation [ Time Frame: Before and immediately following the two experimental sessions ] [ Designated as safety issue: No ]
Pain threshold, pain ratings, and temporal summation [ Time Frame: Before and immediately following an exercise session ] [ Designated as safety issue: No ]
Complete list of historical versions of study NCT01220414 on ClinicalTrials.gov Archive Site
Not Provided
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Attenuation of Pain in Men and Women
Attenuation of Pain in Men and Women: Mechanisms of Exercise-Induced Analgesia
The purpose of this study is to examine opioid and endocannabinoid mechanisms of exercise-induced analgesia in men and women.
Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Basic Science
Pain
  • Drug: Naltrexone,
    50 mg of naltrexone
  • Drug: Placebo
    sugar pill
  • Active Comparator: Men
    Interventions:
    • Drug: Naltrexone,
    • Drug: Placebo
  • Active Comparator: Women
    Interventions:
    • Drug: Naltrexone,
    • Drug: Placebo
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
60
Not Provided
January 2012   (final data collection date for primary outcome measure)

Inclusion Criteria: Healthy men and women

Exclusion Criteria:

  • current cardiac or other chronic diseases (e.g., cancer, diabetes, hypertension, kidney disease); routine use of prescriptive medications; history of vasovagal response to phlebotomy; an allergy to naltrexone; pregnancy; current smokers; current use of recreational drugs; history of substance abuse
Both
18 Years to 40 Years   (Adult)
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01220414
H-2010-0087
Yes
Not Provided
Not Provided
Kelli F. Koltyn, University of Wisconsin
University of Wisconsin, Madison
Not Provided
Not Provided
University of Wisconsin, Madison
October 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP