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Attenuation of Pain in Men and Women

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified October 2010 by University of Wisconsin, Madison.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01220414
First Posted: October 13, 2010
Last Update Posted: October 12, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Wisconsin, Madison
September 28, 2010
October 13, 2010
October 12, 2017
September 2010
January 2012   (Final data collection date for primary outcome measure)
Pain threshold, pain ratings, and temporal summation [ Time Frame: Before and immediately following the two experimental sessions ]
Pain threshold, pain ratings, and temporal summation [ Time Frame: Before and immediately following an exercise session ]
Complete list of historical versions of study NCT01220414 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Attenuation of Pain in Men and Women
Attenuation of Pain in Men and Women: Mechanisms of Exercise-Induced Analgesia
The purpose of this study is to examine opioid and endocannabinoid mechanisms of exercise-induced analgesia in men and women.
Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Basic Science
Pain
  • Drug: Naltrexone,
    50 mg of naltrexone
  • Drug: Placebo
    sugar pill
  • Active Comparator: Men
    Interventions:
    • Drug: Naltrexone,
    • Drug: Placebo
  • Active Comparator: Women
    Interventions:
    • Drug: Naltrexone,
    • Drug: Placebo
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
60
Not Provided
January 2012   (Final data collection date for primary outcome measure)

Inclusion Criteria: Healthy men and women

Exclusion Criteria:

  • current cardiac or other chronic diseases (e.g., cancer, diabetes, hypertension, kidney disease); routine use of prescriptive medications; history of vasovagal response to phlebotomy; an allergy to naltrexone; pregnancy; current smokers; current use of recreational drugs; history of substance abuse
Sexes Eligible for Study: All
18 Years to 40 Years   (Adult)
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT01220414
H-2010-0087
Yes
Not Provided
Not Provided
Kelli F. Koltyn, University of Wisconsin
University of Wisconsin, Madison
Not Provided
Not Provided
University of Wisconsin, Madison
October 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP