We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Screen of DM by OGTT in Subjects Receiving CAG or MDCT for CAD

This study is currently recruiting participants.
Verified September 2017 by TCVGH, Taichung Veterans General Hospital
Sponsor:
ClinicalTrials.gov Identifier:
NCT01198730
First Posted: September 10, 2010
Last Update Posted: September 13, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
TCVGH, Taichung Veterans General Hospital
September 8, 2010
September 10, 2010
September 13, 2017
April 2009
December 2019   (Final data collection date for primary outcome measure)
HbA1c and results of meal tolerance test [ Time Frame: 52 weeks ]
Patient who was diagnosed with DM after an OGTT was asked to follow up HbA1c after 6-12 months. Acarbose was given for those who had HbA1c > 6.5%. After 26 weeks, sitagliptin was given for those who had HbA1c > 7.0%.
Same as current
Complete list of historical versions of study NCT01198730 on ClinicalTrials.gov Archive Site
Hypoglycemia [ Time Frame: 52 weeks ]
Symptoms of hypoglycemia or glucose value below 70 mg/dl after treatment with acarbose
Same as current
Not Provided
Not Provided
 
Screen of DM by OGTT in Subjects Receiving CAG or MDCT for CAD
Screen of Diabetes Mellitus by Oral Glucose Tolerance Test in Subjects Receiving Catheterization or Multi-detector Computed Tomography (MDCT) for Coronary Artery Disease
To determine the glucose regulation status of patients who were suspected to have CAD in central Taiwan.
It had been reported that high prevalence of IGT (impaired glucose tolerance) and unknown DM (diabetes mellitus) in patients with CAD (coronary artery disease). This study aimed to determine the glucose regulation status of patients who were suspected to have CAD in central Taiwan. In general, patient who were admitted for CAG (coronary angiography) or MDCT without known DM were eligible. After informed consent, OGTT (oral glucose tolerance test) was performed to determine the glucose regulation status. Study participants will be requested to complete questionnaires to assess their risk of diabetes and quality of sleep. Patients who were diagnosed as new DM would be asked to follow up after 6-12 months with diet control. Treatment with oral anti-diabetic drug may be needed if HbA1c target was not reached.
Interventional
Not Provided
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
  • Diabetes Mellitus
  • Coronary Artery Disease
Drug: Acarbose
Acarbose 25 mg tid, titrate to 100 mg tid.
Other Name: Glucobay
Acarbose
Acarbose for DM patient with HbA1c > 6.5%. Add on sitagliptin if HbA1c > 7.0% after 26 weeks.
Intervention: Drug: Acarbose
Wang JS, Lee IT, Lee WJ, Lin SY, Fu CP, Ting CT, Lee WL, Liang KW, Sheu WH. Performance of HbA1c and fasting plasma glucose in screening for diabetes in patients undergoing coronary angiography. Diabetes Care. 2013 May;36(5):1138-40. doi: 10.2337/dc12-1434. Epub 2012 Dec 13.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
2000
December 2019
December 2019   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patient received CAG or MDCT for suspect CAD
  • Without DM history

Exclusion Criteria:

  • Known DM
  • Unstable disease condition
  • Pregnancy
Sexes Eligible for Study: All
18 Years to 70 Years   (Adult, Senior)
No
Taiwan
 
 
NCT01198730
C08215
No
Not Provided
Not Provided
TCVGH, Taichung Veterans General Hospital
Taichung Veterans General Hospital
Not Provided
Principal Investigator: Wayne H-H Sheu, MD, PHD Taichung Veterans General Hospital
Taichung Veterans General Hospital
September 2017

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP