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Measurement of Fibrinogen in Patients With Systemic Inflammatory Response Syndrome (SIRS), Sepsis or Chronicle Liver Disease on Intensive Care Units (ICU)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2010 by Johann Wolfgang Goethe University Hospital.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01169168
First Posted: July 26, 2010
Last Update Posted: July 26, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Johann Wolfgang Goethe University Hospital
July 23, 2010
July 26, 2010
July 26, 2010
April 2010
Not Provided
Fibrinogen levels from 5 test methods
  • Clauss fibrinogen
  • PT-Derived fibrinogen
  • immunoturbidimetric method
  • heat-precipitated fibrinogen
  • Schulz fibrinogen
Same as current
No Changes Posted
  • Number of bleedings
  • Number of administered fresh frozen plasma
  • Number of administered erythrocyte concentrates
  • Number of administered thrombocyte concentrates
  • mortality
Same as current
Not Provided
Not Provided
 
Measurement of Fibrinogen in Patients With Systemic Inflammatory Response Syndrome (SIRS), Sepsis or Chronicle Liver Disease on Intensive Care Units (ICU)
Measurement of Fibrinogen in Patients With Systemic Inflammatory Response Syndrome, Sepsis, Chronicle Liver Disease or After Lysis on Intensive Care Units

In this study patients with

  1. chronicle liver diseases

    • primary biliary cirrhosis
    • primary sclerosing cholangitis
    • alcoholic liver cirrhosis
    • hepatitis b or C
    • Wilson's disease
    • cryptogenic cirrhosis
  2. Septic Inflammatory Response Syndrome (SIRS)

    • sepsis
    • septic shock
  3. patients after lysis

should be included

Blood samples will be gathered from the patients to measure fibrinogen with 5 different methods.

The methods are:

  • Clauss fibrinogen
  • PT-Derived fibrinogen
  • immunoturbidimetric method
  • heat-precipitated fibrinogen
  • Schulz fibrinogen

The result of these tests will be correlated with laboratory values which are gathered in routine and the clinical outcomes.

Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:
citrated plasma
Non-Probability Sample
patients in intensive care units of the university hospital
  • SIRS
  • Sepsis
  • Liver Disease
Not Provided
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
250
Not Provided
Not Provided

Inclusion Criteria:

  • SIRS
  • sepsis
  • septic shock
  • chronicle liver disease (MELD-Score >10)
  • patient after lysis
  • patient agrees

Exclusion Criteria:

  • no agreement
Sexes Eligible for Study: All
18 Years to 80 Years   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Germany
 
 
NCT01169168
FibICU
No
Not Provided
Not Provided
Dr. med. Wolfgang Miesbach, Johann Wolfgang Goethe University Hospital
Johann Wolfgang Goethe University Hospital
Not Provided
Not Provided
Johann Wolfgang Goethe University Hospital
July 2010