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Genetic Contributions to Autism Spectrum Disorders

This study is ongoing, but not recruiting participants.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01160783
First Posted: July 12, 2010
Last Update Posted: May 31, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Ingrid Holm, Boston Children's Hospital
July 9, 2010
July 12, 2010
May 31, 2017
April 2007
December 2017   (Final data collection date for primary outcome measure)
Gene expression levels [ Time Frame: At sample collection ]
Not Provided
Complete list of historical versions of study NCT01160783 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
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Genetic Contributions to Autism Spectrum Disorders
Genetic Contributions to Autism Spectrum Disorders
This study is working towards gaining a better understanding of the genetic and environmental factors involved in autism spectrum disorders (ASD), which includes autism, pervasive developmental disorder (PDD), and Asperger's syndrome. The investigators hope that information gained from this study will lead to new ways of diagnosing and treating ASDs.
Participation generally takes less than 2 hours to complete and travel to Children's Hospital Boston is not required. Participants are asked some questions about their medical and family history. The investigators also request permission to review medical records related to the ASD diagnosis. Finally, the investigators obtain a small blood or saliva sample in order to search for genes that may be important in understanding ASD. The investigators can arrange for the blood draw through a participant's physician or a clinical laboratory and saliva samples can be obtained through the mail. The study questions are answered via telephone or mailed questionnaires. There is no cost to participate.
Observational
Observational Model: Family-Based
Time Perspective: Cross-Sectional
Not Provided
Retention:   Samples With DNA
Description:
Whole blood, DNA and RNA and/or Saliva, DNA
Non-Probability Sample
Children with a diagnosis of an Autism Spectrum Disorder (autism, pervasive developmental disorder (PDD), or Asperger's syndrome) and their parents and/or siblings
  • Autism Spectrum Disorder
  • Autism
  • Asperger's Syndrome
  • Pervasive Developmental Disorder
Not Provided
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
240
February 2018
December 2017   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Clinical diagnosis of an Autism Spectrum Disorder (autism, pervasive developmental disorder (PDD), or Asperger's syndrome)
  • Age > 18 months

Exclusion Criteria:

  • Do not have the diagnosis of an ASD
  • Participation in the "Phenotypic and Genetic Risk Factors in ASD" study at Boston Children's Hospital.
Sexes Eligible for Study: All
18 Months and older   (Child, Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT01160783
07-04-0136
No
Not Provided
Plan to Share IPD: No
Ingrid Holm, Boston Children's Hospital
Boston Children’s Hospital
Not Provided
Principal Investigator: Ingrid A Holm, MD, MPH Boston Children’s Hospital
Boston Children’s Hospital
May 2017