Use of Laser Speckle to Study Cutaneous Blood Flow at Exercise in Healthy Subjects (Speckle-move)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01152008
Recruitment Status : Completed
First Posted : June 29, 2010
Last Update Posted : November 1, 2017
Information provided by (Responsible Party):
University Hospital, Angers

June 24, 2010
June 29, 2010
November 1, 2017
June 2010
January 2012   (Final data collection date for primary outcome measure)
Not Provided
Not Provided
Complete list of historical versions of study NCT01152008 on Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
Use of Laser Speckle to Study Cutaneous Blood Flow at Exercise in Healthy Subjects
Evaluation Chez Des Sujets Sains d'Une Nouvelle Technique d'étude de la Microcirculation cutanée
We aim to test the hypothesis that Laser speckle contrast imaging allows for the measurement of cutaneous blood flow during exercise.
Ischemia and post occlusive reactive hyperhemia in the skin is tested in healthy normal subjects at rest and during cycle exercise.
Observational Model: Case-Only
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample
healthy volunteers
Other: tourniquet ischemia
Recording of cutaneous blood flow on the forearm at rest and during cycle exercise 50W before and following tourniquet ischemia
Other Names:
  • laser doppler flowmetry
  • Transcutaneous PO2
  • Near infra-red spectrometry
healthy volunteers
Intervention: Other: tourniquet ischemia
Mahé G, Haj-Yassin F, Rousseau P, Humeau A, Durand S, Leftheriotis G, Abraham P. Distance between laser head and skin does not influence skin blood flow values recorded by laser speckle imaging. Microvasc Res. 2011 Nov;82(3):439-42. doi: 10.1016/j.mvr.2011.06.014. Epub 2011 Jul 14.

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
January 2012
January 2012   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Healthy volunteers
  • Affiliation to the French health system

Exclusion Criteria:

  • Any disease or chronic treatment
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
CHU P 2010-05
Not Provided
Not Provided
University Hospital, Angers
University Hospital, Angers
Not Provided
Principal Investigator: Guillaume MAHE, MD University Hospital in Angers
University Hospital, Angers
July 2010