Effect Study of Optimized Intervention to Heroin Addicts

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01144390
Recruitment Status : Unknown
Verified March 2011 by Shanghai Mental Health Center.
Recruitment status was:  Active, not recruiting
First Posted : June 15, 2010
Last Update Posted : March 11, 2011
Information provided by:
Shanghai Mental Health Center

June 11, 2010
June 15, 2010
March 11, 2011
April 2010
June 2011   (Final data collection date for primary outcome measure)
treatment retention [ Time Frame: 12 months ]
retaining patients in the methadone maintenance treatment during and after the study.
treatment retention [ Time Frame: 12 months ]
Complete list of historical versions of study NCT01144390 on Archive Site
in-treatment performance. [ Time Frame: 12 months ]
treatment performance of addicts include: treatment sessions during the study, negative urine specimens, drop-out rate, severity of ASI,scores of HIV-related high risk sexual behavior, the temperature and character inventory, perceived stigma scale, self-esteem inventory,self efficacy, social support scores,drug use from self-report from baseline to 3 month and 6 month.
in-treatment performance. [ Time Frame: 12 months ]
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Effect Study of Optimized Intervention to Heroin Addicts
Barriers and Effect of Optimizing Intervention Protocols for Heroin Dependence in Community-based Methadone Maintenance Treatment (MMT): a Cohort Study
The purpose of this study is to explore barriers and determine whether optimizing protocol is effective in the treatment of heroin dependence in community-based MMT clinics.
Drug dependence is one of the most serious public health problems worldwide. In China, among more than 100, 0000 registered drug addicts mostly are heroin dependence. Drug dependence post great risks to physical condition, their family and society, and can lead to infectious disease transmission. Though almost 500 MMT clinics which can offer MMT service to heroin addicts have been set up, there are still some problems, for example, poor compliance, high rate of dropping out and relapse which affect the service delivery to them. The guideline developed by WHO focused on psychotherapy to opiate addicts with MMT. So delivery of a set of comprehensive, integrated psychotherapy to opiate addicts is very critical in such methadone clinics.
Not Applicable
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Heroin Dependence
  • Behavioral: cognitive behavioral therapy
    cognitive behavioral therapy, one session per week and psycho-education lecture in group once per month
  • Drug: methadone maintenance treatment
    methadone maintenance treatment
  • Experimental: CBT plus MMT
    cognitive behavioral therapy for heroin addicts with methadone maintenance treatment
    • Behavioral: cognitive behavioral therapy
    • Drug: methadone maintenance treatment
  • Active Comparator: methadone maintenance treatment
    methadone maintenance treatment for heroin addicts
    Intervention: Drug: methadone maintenance treatment
Pan S, Jiang H, Du J, Chen H, Li Z, Ling W, Zhao M. Efficacy of Cognitive Behavioral Therapy on Opiate Use and Retention in Methadone Maintenance Treatment in China: A Randomised Trial. PLoS One. 2015 Jun 24;10(6):e0127598. doi: 10.1371/journal.pone.0127598. eCollection 2015.

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Unknown status
Same as current
June 2011
June 2011   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • clinical diagnosis of heroin dependence
  • must be able to take methadone

Exclusion Criteria:

  • schizophrenia and mood disorder
  • physical disabilities who could not come to take part in psychotherapy sessions.
Sexes Eligible for Study: All
18 Years to 65 Years   (Adult)
Contact information is only displayed when the study is recruiting subjects
Not Provided
Not Provided
Min ZHAO, Shanghai Mental Health Center
Shanghai Mental Health Center
Not Provided
Principal Investigator: min ZHAO, Ph.D. Shanghai Mental Health Center
Shanghai Mental Health Center
March 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP