Examination of Gastric Emptying in Children

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01133691
Recruitment Status : Completed
First Posted : May 31, 2010
Last Update Posted : January 18, 2012
Information provided by (Responsible Party):
University Children's Hospital, Zurich

May 11, 2010
May 31, 2010
January 18, 2012
May 2010
February 2011   (Final data collection date for primary outcome measure)
Gastric emptying time [ Time Frame: 6 hours ]
Time after food/fluid ingestion when gastric volume after overnight fast is achieved, as measured by volumetry of magnetic resonance scans
Same as current
Complete list of historical versions of study NCT01133691 on Archive Site
  • gastric volume after fasting [ Time Frame: 6 hours ]
  • gastric antral area [ Time Frame: 6 hours ]
  • visual analog scale of thirst/hunger [ Time Frame: 6 hours ]
Same as current
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Examination of Gastric Emptying in Children
Examination of Gastric Emptying With Magnetic Resonance Imaging and Ultrasonography
  • Background: Fasting is mandatory for safety of anesthesia in elective surgery and imaging but gives rise to discomfort, hunger and thirst especially in children. Internationally accepted fasting times are often prolonged because of organisational delay in operating theatre.
  • Hypothesis: Clear fluids can be ingested until an imaginary anesthesia induction time without enlarging the residual gastric contents compared to overnight fast. There is no difference between residual gastric contents after 4 hours of fasting after a light meal compare to 6 hours in healthy children.
  • Examination of gastric volume using magnetic resonance imaging after overnight fasting and subsequent scans after either clear fluid intake or intake of a standard breakfast are performed in children aged 6 - 12 years. Time course after fluid intake is followed with scans every half hour for 2 hours. In the breakfast group 4 versus 6 hours fasting time will be simulated, e. g. intake of clear fluid is allowed for 2 versus 4 hours after the meal. Volume of gastric contents will be compared with a standardized ultrasonographic view of the stomach.
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Observational Model: Case-Only
Time Perspective: Prospective
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Non-Probability Sample
healthy children aged 6 - 12 years old
Gastric Emptying
Dietary Supplement: clear fluid, light breakfast
clear fluid 7 ml/kg, breakfast consisting of yoghurt, muesli, mild
healthy children aged 6 - 12 years
Intervention: Dietary Supplement: clear fluid, light breakfast
Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
February 2011
February 2011   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • age 6 - 12 years
  • ASA I or II

Exclusion Criteria:

  • gastrointestinal pathology
  • claustrophobia
  • implants like pacemaker, ventriculoperitoneal shunt etc
  • symptomatic or relevant cardiac, renal or metabolic disease
Sexes Eligible for Study: All
6 Years to 12 Years   (Child)
Contact information is only displayed when the study is recruiting subjects
KEK-ZH-Nr. 2009-0147
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University Children's Hospital, Zurich
University Children's Hospital, Zurich
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Principal Investigator: Achim J Schmitz, MD Children's University Hospital Zurich, Anesthesiology
University Children's Hospital, Zurich
January 2012