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Cell Culture of Glioma Specimens for in Vitro Preclinical Studies

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ClinicalTrials.gov Identifier: NCT01125826
Recruitment Status : Unknown
Verified April 2009 by Albany Medical College.
Recruitment status was:  Recruiting
First Posted : May 19, 2010
Last Update Posted : June 27, 2011
Sponsor:
Information provided by:
Albany Medical College

May 18, 2010
May 19, 2010
June 27, 2011
April 2009
April 2012   (Final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT01125826 on ClinicalTrials.gov Archive Site
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Cell Culture of Glioma Specimens for in Vitro Preclinical Studies
Primary Cell Culture of Surgical Glioma Specimens for Invitro Preclinical Studies

The purpose of this study is to culture primary human brain tumor cells with the specific aims of:

  1. Develop primary cultures from human brain tumor surgical specimens
  2. Determine the genetic and molecular fingerprints of brain tumors that may have prognostic significance
  3. Delineate the mechanisms underlying oncogenesis of brain tumors.
  4. Perform in vitro assays with brain tumor derived primary cultures to assess the efficacy of novel therapeutic agents.
Not Provided
Observational
Observational Model: Case-Only
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:
All subjects will be give permission for specimen storage by signing a separate permission on the informed consent. All specimens will be stored at a tissue bank for an unspecified amount of time.
Probability Sample
Patients 18 years of age or older undergoing surgical resection for gliomas.
Brain Tumor
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
50
Same as current
June 2012
April 2012   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patients 18 years of age or older undergoing surgical resection for glioma

Exclusion Criteria:

  • Under 18 years of age
Sexes Eligible for Study: All
18 Years and older   (Adult, Older Adult)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT01125826
2536
No
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Yu-Hung Kuo, MD, Neurosciences Institute, Albany Medical College
Albany Medical College
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Albany Medical College
April 2009