Daily Monitoring of Exhaled Nitric Oxide in Asthmatic Patients

This study has been completed.

Sponsor:

Collaborator:

Azienda Ospedaliera Universitaria Policlinico

Information provided by:

Universita di Verona

ClinicalTrials.gov Identifier:

NCT01113853

First received: April 28, 2010

Last updated: April 30, 2010

Last verified: January 2007

History of Changes

Tracking Information

First Received Date ^ICMJE

April 28, 2010

Last Updated Date

April 30, 2010

Start Date ^ICMJE

January 2007

Primary Completion Date

Not Provided

Current Primary Outcome Measures ^ICMJE

Not Provided

Original Primary Outcome Measures ^ICMJE

Not Provided

Change History

Complete list of historical versions of study NCT01113853 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Not Provided

Original Secondary Outcome Measures ^ICMJE

Not Provided

Current Other Outcome Measures ^ICMJE

Not Provided

Original Other Outcome Measures ^ICMJE

Not Provided

Descriptive Information

Brief Title ^ICMJE

Daily Monitoring of Exhaled Nitric Oxide in Asthmatic Patients

Official Title ^ICMJE

Daily Monitoring of Exhaled Nitric Oxide in Asthmatic Patients Stopping Anti-inflammatory Treatment

Brief Summary

Previous studies have demonstrated that exhaled nitric oxide can be useful to monitor the efficacy of anti-inflammatory treatment as well as to predict a risk of asthma relapse in asthmatic patients.

The aim of the present study is to evaluate the time course of exhaled nitric oxide in mild asthmatic patients, stopping regular treatment with inhaled corticosteroids, if it is possible, in relationship with symptoms and lung function.

Detailed Description

All patients were evaluated with pulmonary lung function, exhaled nitric oxide and peak expiratory flow (PEF) and fill in a personal diary for the first two weeks when patients are in treatment; the same evaluation will be made for other four weeks without treatment.

Study Type ^ICMJE

Observational

Study Design ^ICMJE

Observational Model: Case-Only
Time Perspective: Cross-Sectional

Target Follow-Up Duration

Not Provided

Biospecimen

Not Provided

Sampling Method

Probability Sample

Study Population

children with asthma visited in the outpatients clinic at University of Verona were invited to participate to the study

Condition ^ICMJE

Asthma

Intervention ^ICMJE

Not Provided

Study Groups/Cohorts

Not Provided

Publications *

Not Provided

* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Completed

Enrollment ^ICMJE

Completion Date

January 2010

Primary Completion Date

Not Provided

Eligibility Criteria ^ICMJE

Inclusion Criteria:

mild asthmatic treated with low dose inhaled steroids for whom it has to be considered stop of steroid treatment according to GINA guidelines

Exclusion Criteria:

age < 5 years
chronic respiratory diseases

Sex/Gender

Sexes Eligible for Study:

All

Ages

5 Years and older (Child, Adult, Senior)

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Listed Location Countries ^ICMJE

Italy

Removed Location Countries

Administrative Information

NCT Number ^ICMJE

NCT01113853

Other Study ID Numbers ^ICMJE

AOV 1360

Has Data Monitoring Committee

U.S. FDA-regulated Product

Not Provided

Plan to Share Data

Not Provided

IPD Description

Not Provided

Responsible Party

attilio L Boner, Università di Verona

Study Sponsor ^ICMJE

Universita di Verona

Collaborators ^ICMJE

Azienda Ospedaliera Universitaria Policlinico

Investigators ^ICMJE

Principal Investigator:

Giorgio L Piacentini, MD

Universita di Verona

PRS Account

Universita di Verona

Verification Date

January 2007

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP

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