Daily Monitoring of Exhaled Nitric Oxide in Asthmatic Patients

Tracking Information
First Submitted Date	April 28, 2010
First Posted Date	April 30, 2010
Last Update Posted Date	May 3, 2010
Study Start Date	January 2007
Primary Completion Date	Not Provided
Current Primary Outcome Measures	Not Provided
Original Primary Outcome Measures	Not Provided
Change History	Complete list of historical versions of study NCT01113853 on ClinicalTrials.gov Archive Site
Current Secondary Outcome Measures	Not Provided
Original Secondary Outcome Measures	Not Provided
Current Other Outcome Measures	Not Provided
Original Other Outcome Measures	Not Provided
Descriptive Information
Brief Title	Daily Monitoring of Exhaled Nitric Oxide in Asthmatic Patients
Official Title	Daily Monitoring of Exhaled Nitric Oxide in Asthmatic Patients Stopping Anti-inflammatory Treatment
Brief Summary	Previous studies have demonstrated that exhaled nitric oxide can be useful to monitor the efficacy of anti-inflammatory treatment as well as to predict a risk of asthma relapse in asthmatic patients. The aim of the present study is to evaluate the time course of exhaled nitric oxide in mild asthmatic patients, stopping regular treatment with inhaled corticosteroids, if it is possible, in relationship with symptoms and lung function.
Detailed Description	All patients were evaluated with pulmonary lung function, exhaled nitric oxide and peak expiratory flow (PEF) and fill in a personal diary for the first two weeks when patients are in treatment; the same evaluation will be made for other four weeks without treatment.
Study Type	Observational
Study Design	Observational Model: Case-Only; Time Perspective: Cross-Sectional
Target Follow-Up Duration	Not Provided
Biospecimen	Not Provided
Sampling Method	Probability Sample
Study Population	children with asthma visited in the outpatients clinic at University of Verona were invited to participate to the study
Condition	Asthma
Intervention	Not Provided
Study Groups/Cohorts	Not Provided
Publications *	Not Provided
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
Recruitment Information
Recruitment Status	Completed
Actual Enrollment; (submitted: April 28, 2010)	40
Original Actual Enrollment	Same as current
Actual Study Completion Date	January 2010
Primary Completion Date	Not Provided
Eligibility Criteria	Inclusion Criteria: mild asthmatic treated with low dose inhaled steroids for whom it has to be considered stop of steroid treatment according to GINA guidelines Exclusion Criteria: age < 5 years; chronic respiratory diseases
Sex/Gender	Sexes Eligible for Study: All
Ages	5 Years and older (Child, Adult, Senior)
Accepts Healthy Volunteers	No
Contacts	Contact information is only displayed when the study is recruiting subjects
Listed Location Countries	Italy
Removed Location Countries
Administrative Information
NCT Number	NCT01113853
Other Study ID Numbers	AOV 1360
Has Data Monitoring Committee	No
U.S. FDA-regulated Product	Not Provided
IPD Sharing Statement	Not Provided
Responsible Party	attilio L Boner, Università di Verona
Study Sponsor	Universita di Verona
Collaborators	Azienda Ospedaliera Universitaria Policlinico
Investigators	Principal Investigator: Giorgio L Piacentini, MD Universita di Verona
PRS Account	Universita di Verona
Verification Date	January 2007