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Incision and Drainage Versus Needle Aspiration in Soft Tissue Abscesses

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ClinicalTrials.gov Identifier: NCT01085929
Recruitment Status : Completed
First Posted : March 12, 2010
Last Update Posted : March 12, 2010
Information provided by:

March 10, 2010
March 12, 2010
March 12, 2010
August 2008
November 2009   (Final data collection date for primary outcome measure)
Successful drainage of abscess [ Time Frame: 7 days ]
Clinical outcome at 7 days
Same as current
No Changes Posted
  • Successful drainage of abscess [ Time Frame: 2 days ]
    Healing of abscess following drainage procedure at day 2
  • Ability to evacuate purulence from abscess [ Time Frame: Day 1 ]
    Amount of purulence produced by drainage procedure on day 1
Same as current
Not Provided
Not Provided
Incision and Drainage Versus Needle Aspiration in Soft Tissue Abscesses
Ultrasound Guided Needle Drainage Versus Formal Incision and Drainage of Superficial Soft Tissue Abscesses in the Emergency Department Setting
The incidence of skin and soft tissue infections has increased dramatically over the last decade, in part due to increased prevalence of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). Incision and drainage (I&D) is considered the primary intervention, however some clinicians prefer ultrasound guided needle aspiration (US Asp). The investigators performed a randomized trial comparing US Asp to I&D for uncomplicated skin and soft tissue abscesses, with a subgroup analysis of patients with CA-MRSA.
Not Provided
Phase 3
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
  • Abscess
  • Cellulitis
  • Procedure: Incision and Drainage
    Surgical incision of the skin surface followed by expression of purulence with or without debridement or manual exploration of abscess cavity.
  • Procedure: Ultrasound Guided Aspiration
    Ultrasound is used to identify the abscess cavity. An 18 gauge needle is introduced into the abscess cavity and manual aspiration of the abscess contents is attempted.
  • Active Comparator: Incision and Drainage
    Abscess underwent incision and drainage
    Intervention: Procedure: Incision and Drainage
  • Active Comparator: Ultrasound guided needle aspiration
    Ultrasound was used to identify the abscess location. A needle was introduced into the abscess cavity and aspiration of the contents were attempted.
    Intervention: Procedure: Ultrasound Guided Aspiration
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
December 2009
November 2009   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • presenting to emergency department with skin abscess
  • abscess required surgical drainage
  • healthy appearing

Exclusion Criteria:

  • pregnant
  • unable to give consent
  • abscess located in oral cavity
  • abscess located on genitalia
  • abscess located intra-gluteal at coccyx
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
United States
Not Provided
Not Provided
Romolo Gaspari, University of Massachusetts
University of Massachusetts, Worcester
Beth Israel Deaconess Medical Center
Principal Investigator: Romolo Gaspari, MD, PhD University of Massachusetts, Worcester
University of Massachusetts, Worcester
March 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP