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Comparison of Lidocaine and Remifentanil for the Effect on Responses to the Endotracheal Tube During Emergence From General Anesthesia

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01082458
First Posted: March 8, 2010
Last Update Posted: November 19, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Yonsei University
March 4, 2010
March 8, 2010
November 19, 2010
February 2010
July 2010   (Final data collection date for primary outcome measure)
Comparison of lidocaine and remifentanil for the effect on responses to the endotracheal tube during emergence from general anesthesia
The incidence and the grade of cough during emergence from general anensthesia between remifentanil TCI group and lidocaine IV administration group.
Same as current
Complete list of historical versions of study NCT01082458 on ClinicalTrials.gov Archive Site
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Comparison of Lidocaine and Remifentanil for the Effect on Responses to the Endotracheal Tube During Emergence From General Anesthesia
Comparison of Lidocaine and Remifentanil for the Effect on Responses to the Endotracheal Tube During Emergence From General Anesthesia
Target concentration infusion(TCI) of remifentanil (2.0ng/ml) suppresses the cough induced by endotracheal tube more effectively than intravenous administration of lidocaine (1.5mg/kg).
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Interventional
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Primary Purpose: Prevention
Thyroidectomy
Drug: remifentanil / lidocaine

Remifentanil TCI group : target controlled infusion of 2.0ng/ml of remifentanil on end of surgery.

Lidocaine IV group : Intravenous administration of 1.5mg/kg of lidocaine on end of surgery.

Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
67
July 2010
July 2010   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Females older than 20 years old

Exclusion Criteria:

  • Patients with acute or chronic respiratory disease, hypertension, gastro-esophageal reflux disease, having preoperative sedatives or mucolytics, and current smoker.
Sexes Eligible for Study: Female
20 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
 
NCT01082458
4-2009-0519
Yes
Not Provided
Not Provided
Jung-Lim Lee / Assistant Professor, Anesthesiology and Pain Medicine
Yonsei University
Not Provided
Not Provided
Yonsei University
November 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP