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Cognitive Dysfunction After Aneurysmal Subarachnoid Haemorrhage

This study is currently recruiting participants.
Verified November 2017 by George KC Wong, Chinese University of Hong Kong
Sponsor:
ClinicalTrials.gov Identifier:
NCT01038193
First Posted: December 23, 2009
Last Update Posted: November 14, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
George KC Wong, Chinese University of Hong Kong
December 22, 2009
December 23, 2009
November 14, 2017
March 2009
March 2020   (Final data collection date for primary outcome measure)
Cognitive dysfunction [ Time Frame: 3 and 12 months ]
Montreal Cognitive Assessment
Cognitive dysfunction [ Time Frame: 9 months ]
Complete list of historical versions of study NCT01038193 on ClinicalTrials.gov Archive Site
  • Neurological Outcome [ Time Frame: 3 and 12 months ]
    Modified Rankin Scale
  • Generic Quality of Life [ Time Frame: 3 and 12 months ]
    ShortForm36(SF-36)
  • Activity of Daily Living [ Time Frame: 3 and 12 months ]
    Barthel Index
  • Disease-specific Quality of Life [ Time Frame: 3 and 12 months ]
    Stroke-specific-QOL
  • Functional Outcome [ Time Frame: 3 and 12 months ]
    Functional Independent Measure (FIM)
  • Modified Rankin Scale [ Time Frame: 9 months ]
  • SF-36 [ Time Frame: 9 months ]
  • Lawton-Instrumental-ADL [ Time Frame: 9 months ]
Not Provided
Not Provided
 
Cognitive Dysfunction After Aneurysmal Subarachnoid Haemorrhage
Cognitive Dysfunction After Aneurysmal Subarachnoid Haemorrhage
This is a longitudinal, multi-center, prospective study of aneurysmal subarachnoid haemorrhage patients in neurosurgical units in Hong Kong.
The investigators aim to recruit a total of 240 aneurysmal subarachnoid haemorrhage patients. The schedule for neuropsychological and functional assessments will be phased in at the second to third week, the third month, and the twelve months after the initial haemorrhage.
Observational
Observational Model: Case-Only
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample
Aneurysmal subarachnoid hemorrhage patients
Cognitive Dysfunction
Other: Cognitive assessment
Cognitive and functional assessments at 2-4 weeks, 3 months and 12 months.
Other Name: Cognition
aSAH patients
Cognitive assessment
Intervention: Other: Cognitive assessment

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
600
March 2021
March 2020   (Final data collection date for primary outcome measure)

Inclusion criteria

  1. Spontaneous subarachnoid haemorrhage with intracranial aneurysms as aetiology
  2. Admission within 96 hours of ictus
  3. Aged between 21 and 75 years
  4. A speaker of Chinese (Mandarin or Cantonese)
  5. Informed consent from patients or their legally acceptable representatives

Exclusion criteria

  1. History of previous cerebrovascular disease or neurological disease other than intracranial aneurysm
  2. History of neurosurgical operation prior to ictus
Sexes Eligible for Study: All
21 Years to 75 Years   (Adult, Senior)
Yes
Contact: George KC Wong (852) 26321316
Contact: Shirley Chiu (852) 26322624
China
 
 
NCT01038193
GW004
Yes
Not Provided
Plan to Share IPD: No
George KC Wong, Chinese University of Hong Kong
Chinese University of Hong Kong
Not Provided
Principal Investigator: George KC Wong Division of Neurosurgery, CUHK
Chinese University of Hong Kong
November 2017