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The Effect of Exposure to Maternal Human Milk Odor on Physiological State of Preterms.

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ClinicalTrials.gov Identifier: NCT01012505
Recruitment Status : Unknown
Verified November 2009 by Sheba Medical Center.
Recruitment status was:  Not yet recruiting
First Posted : November 13, 2009
Last Update Posted : November 13, 2009
Sponsor:
Collaborator:
Information provided by:

November 11, 2009
November 13, 2009
November 13, 2009
December 2009
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No Changes Posted
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The Effect of Exposure to Maternal Human Milk Odor on Physiological State of Preterms.
The Effect of Exposure to Maternal Human Milk Odor on Physiological State of Preterms.

Mammalian fetal sensory development comes in an invariant series, with the tactile/kinesthetic and chemosensory systems the earliest functioning and responsive to stimulation, implicating the importance of these foundational sensory systems for later development. Olfaction is essential for neonatal behavioral adaptation in many mammals, including humans. Experiments show that newborns recognize, and are soothed by, the smell of amniotic fluid. Provision of the mother's smell with breast pads, handkerchiefs she has worn, breast milk on a cotton ball or cotton applicator, or other means of providing odor and taste input can facilitate recognition by the infant's mother at a later time and does not appear to be detrimental to the stability of the infant.

Provision of the odor and taste of the mother's milk has been shown to facilitate the infant's mouthing, sucking, arousal, and calming from irritability, especially in preparation for oral feeding. Using 24 hour monitor analysis and cortisol saliva measurements, we will provide quantitive analysis to the effect of smell.

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Observational
Observational Model: Cohort
Time Perspective: Prospective
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Non-Probability Sample
preterm infants at least 1 weekk of age no active disease or treatment (like respiratory support) place in incubator
  • Health Preterm Infants With no Active Disease
  • Human Milk Nutrition
  • Incubator Stay
Other: adding pad with maternal milk in hte incubator

2 days prior to intervention - recording infants data and taking saliva cortisol adding pad with maternal milk - during 2 days - recording infants data and taking saliva cortisol.

stopping intervention and for other 2 days recording infants data and taking saliva cortisol

20 preterm infants
20 preterm infants without active disease
Intervention: Other: adding pad with maternal milk in hte incubator
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
20
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Inclusion Criteria:

  • preterm infants at least 1 week of age
  • no active disease or treatment (like respiratory support)
  • place in incubator

Exclusion Criteria:

  • active disease or treatment
Sexes Eligible for Study: All
up to 4 Weeks   (Child)
No
Contact information is only displayed when the study is recruiting subjects
Israel
 
 
NCT01012505
SHEBA-09-7392-AM-CTIL
No
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Dr. Ayala Maayan, Sheba Medical Cener
Sheba Medical Center
Tel Aviv University
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Sheba Medical Center
November 2009