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Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana

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ClinicalTrials.gov Identifier: NCT01001741
Recruitment Status : Completed
First Posted : October 27, 2009
Last Update Posted : September 17, 2015
Information provided by (Responsible Party):
University of Pennsylvania

October 23, 2009
October 27, 2009
September 17, 2015
June 2008
August 2009   (Final data collection date for primary outcome measure)
HIV medication adherence [ Time Frame: Monthly ]
Same as current
Complete list of historical versions of study NCT01001741 on ClinicalTrials.gov Archive Site
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Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana
A Pilot Study of Cellular Phone Text Message Reminders to Improve HIV Medication Adherence at Independence Surgery Clinic Gaborone, Botswana
While medication adherence is critical to successful treatment of HIV, there are few studies of interventions demonstrating improvements in adherence. This may be a particular challenge in the developing world, which has a larger burden of HIV but fewer resources than industrialized countries. The investigators propose a randomized controlled trial of cellular phone text message reminders to improve medication adherence. Our pilot study will be set in a large HIV clinic in Gaborone, Botswana, where Penn researchers have collaborated on research projects in the past. The primary study outcome will be antiretroviral medication adherence.
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Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care
HIV Infections
Other: Cell phone text message
We will use cellular text messages to remind patients of impending drug prescription refills and scheduled visits to their healthcare provider.
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Reid MJ, Dhar SI, Cary M, Liang P, Thompson J, Gabaitiri L, Steele K, Mayisela S, Dickinson D, Friedman H, Linkin DR, Steenhoff AP. Opinions and attitudes of participants in a randomized controlled trial examining the efficacy of SMS reminders to enhance antiretroviral adherence: a cross-sectional survey. J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):e86-8. doi: 10.1097/QAI.0b013e3182a9c72b.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
August 2009
August 2009   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • HIV infected
  • 21 years of age or older

Exclusion Criteria:

  • Subjects who do not intend to have continuous follow-up care and monthly medication refills at Independence Surgery for at least the next six months
Sexes Eligible for Study: All
21 Years and older   (Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
NIH: P30 AI 045008
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University of Pennsylvania
University of Pennsylvania
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Study Director: Darren Linkin, MD University of Pennsylvania
Principal Investigator: Harvey Friedman, MD University of Pennsylvania
Study Director: James Thompson, MBA Wharton Business School, UPenn
Study Director: Andrew Steenhoff University of Pennsylvania
University of Pennsylvania
June 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP