'Questions About Quitting' Smoking Cessation Trial (Q2)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00992264
Recruitment Status : Completed
First Posted : October 9, 2009
Results First Posted : August 15, 2014
Last Update Posted : October 13, 2017
University of Michigan
Information provided by (Responsible Party):
Kaiser Permanente

October 7, 2009
October 9, 2009
April 4, 2014
August 15, 2014
October 13, 2017
May 2010
November 2012   (Final data collection date for primary outcome measure)
  • Smoking Abstinence [ Time Frame: 12 months ]
    7 day point prevalent abstinence
  • Treatment Utilization for Smoking Cessation [ Time Frame: 12 months ]
    confirmed use of pharmacotherapy or enrollment in health plan-sponsored counseling program
  • Tobacco Use [ Time Frame: 2, 6, 12 months ]
  • Treatment Utilization for Smoking Cessation [ Time Frame: 2, 6, 12 months ]
Complete list of historical versions of study NCT00992264 on Archive Site
Not Provided
  • Quit Attempts [ Time Frame: 2, 6, 12 months ]
  • Motivation to Quit Smoking [ Time Frame: 2, 6, 12 months ]
Not Provided
Not Provided
'Questions About Quitting' Smoking Cessation Trial
Optimizing an Online Motivational Tobacco Cessation Program
The current study tested the effectiveness of four potentially important tailoring factors (decisional framework, self-efficacy, navigation autonomy, and proactive outreach) in the context of an online motivational intervention for smoking cessation. A fifth factor was originally planned by dropped during intervention development due to confounds with the other planned factors. Information learned from this study will inform how to best design an online interventions for smoking cessation. Participants were recruited from a large, regional U.S. health plan. Using a full factorial design to screen for important main effects and 2-way interactions, participants were randomized to receive one of 16 different experimental factor combinations and followed for one year to assess program impact on smokers' use of empirically-validated cessation treatment and abstinence.
The current study is a factorial screening experiment, consistent with the Multiphase Optimization Strategy. Participants were randomly assigned to one of 16 different combinations of the 4 experimental factors. Each factor was explored on 2 contrasting levels. Each contrasting factor level was then compared to the other, resulting in 4 analytic arms. Within each arm, all participants (n = 1865) were analyzed to determine the relative effect of each contrasting factor level on the primary and secondary outcomes of interest.
Not Applicable
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
  • Behavioral: Message Tone
    All participants receive an tailored, online smoking cessation program. Participants in this intervention group either receive content written in a prescriptive tone or a motivational tone.
  • Behavioral: Navigation
    Persons in this arm either have their ability to navigate the site dictated for them based on their readiness to quit smoking or they are able to freely navigate through the website.
  • Behavioral: Proactive Outreach
    Persons receive periodic, proactively delivered email reminders to visit the intervention website.
  • Behavioral: Testimonials
    People receive a personally-tailored testimonial as part of their online smoking cessation program.
  • Experimental: Message Tone

    Prescriptive or Motivational

    Persons are randomized to receive intervention content written in either a prescriptive or motivational tone.

    Intervention: Behavioral: Message Tone
  • Experimental: Testimonials
    Persons are randomized to receive a personally tailored testimonial or not.
    Intervention: Behavioral: Testimonials
  • Experimental: Navigation

    Dictated or Non-Dictated

    Persons are randomly assigned to be able to freely navigate the website or to have their navigation of the website pre-determined based on their baseline readiness to quit smoking.

    Intervention: Behavioral: Navigation
  • Experimental: Proactive Outreach

    Email or No-Email communication

    Persons are randomized to receive periodic email reminders to return to the intervention website or not.

    Intervention: Behavioral: Proactive Outreach

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
November 2013
November 2012   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Member of Group Health Cooperative
  • Currently Smoking at Least 5 Cigarettes/Day
  • Access to Email and the Internet
  • Read and Write English
  • 18 years or older
  • Not currently receiving tobacco cessation treatment
  • Capable of participating in online and phone surveys

Exclusion Criteria:

  • Persons will be excluded if they do not meet above criteria
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
United States
R01CA138598( U.S. NIH Grant/Contract )
Not Provided
Not Provided
Kaiser Permanente
Kaiser Permanente
University of Michigan
Principal Investigator: Jennifer B McClure, PhD Group Health Research Institute
Kaiser Permanente
October 2017

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP